Species: Hu, Rt
Applications: Flow, ICC/IF, IHC, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Bv, Ch
Applications: WB, ELISA, Func, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Function: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4; Subcellular location: Nucleus
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
6613 |
Alternate Names |
- HSMT3
- MGC117191
- sentrin 2
- Sentrin-2
- small ubiquitin-like modifier 2
- small ubiquitin-related modifier 2
- SMT3 (suppressor of mif two 3, yeast) homolog 2
- SMT3 homolog 2
- SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
- SMT3 suppressor of mif two 3 homolog 2 (yeast)
- Smt3A
- SMT3A
- SMT3B
- SMT3H2
- SUMO-2
- SUMO3
- SUMO-3
- Ubiquitin-like protein SMT3A
- ubiquitin-like protein SMT3B
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