Species: Hu
Applications: WB, ICC/IF, IHC, IP, ChIP
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, Func, ICC/IF, IHC, IP, B/N, ChIP
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE, Bioactivity
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
RbAp48 encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes.
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
5928 |
Alternate Names |
- CAF-1 subunit C
- CAF-I p48
- Chromatin assembly factor 1 subunit C
- Chromatin assembly factor I p48 subunit
- chromatin assembly factor/CAF-1 p48 subunit
- histone-binding protein RBBP4
- MSI1 protein homolog
- Nucleosome-remodeling factor subunit RBAP48
- NURF55
- RbAp48
- RBAP48
- RBBP-4
- retinoblastoma binding protein 4
- Retinoblastoma-binding protein 4CAF-I 48 kDa subunit
- Retinoblastoma-binding protein p48
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