Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Description
PIM2 belongs to a family of cytoplasmic serine/threonine protein kinases that consists of two other members, PIM1 and PIM3. Expression of this protein is regulated by hematopoietic cytokines. PIM2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. It is also highly expressed in human leukemic and lymphoma cell lines. The gene is also expressed in primary spermatocytes. The results suggest a role for PIM2 in proliferating cells as well as during meiosis. PIM2 is thought to be a mediator of p53 mediated apoptosis inhibition by interleukin 3, which supports its role in the formation of various tumours including lymphomas.
Bioinformatics
| Entrez |
Human
Mouse
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
11040 |
| Alternate Names |
- EC 2.7.11.1
- pim-2 oncogene
- Pim-2h
- pim-2h
- proto-oncogene Pim-2 (serine threonine kinase)
- serine/threonine protein kinase pim-2
- serine/threonine-protein kinase pim-2
|
Research Areas for PIM2
Find related products by research area and learn more about each of the different research areas below.
Protein Kinase
