NEIL2 Products

Description

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM]

Bioinformatics

Uniprot	AAH13964 Human NM_145043 Human NP_001129218 Human NP_001129219 Human NP_659480.1 Human Q969S2 Human
Product By Gene ID	252969
Alternate Names	DNA glycosylase/AP lyase Neil2 EC 3.2.2.- EC 4.2.99.18 endonuclease 8-like 2 Endonuclease VIII-like 2 FLJ31644 MGC2832 MGC4505 NEH2DNA-(apurinic or apyrimidinic site) lyase Neil2 nei endonuclease VIII-like 2 (E. coli) Nei homolog 2 nei like 2 (E. coli) nei like 2 NEI2 Nei-like protein 2

Research Areas for NEIL2

Find related products by research area and learn more about each of the different research areas below.

Base Excision Repair
DNA Repair