NBR1 Products

Description

NBR1 is encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene.

Bioinformatics

Uniprot	NP_005890 Human NP_005890.2 Human NP_114064 Human NP_114068 Human P97432 Mouse Q14596 Human
Product By Gene ID	4077
Alternate Names	Cell migration-inducing gene 19 protein FLJ98272 KIAA0049CA125 M17S2FLJ55359,1A1-3B Membrane component chromosome 17 surface marker 2,1A13B membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigenCA125) migration-inducing protein 19 Neighbor of BRCA1 gene 1 protein neighbor of BRCA1 gene 1 next to BRCA1 gene 1 protein Protein 1A1-3B

Related NBR1 Blog Posts

Check out the latest blog posts on NBR1.

Why LC3B Antibodies Make Ideal Autophagosomes Membrane Markers The human form of microtubule-associated protein light chain 3 (LC3) is expressed as 3 splice variants LC3A, LC3B, and LC3C.1 LC3B is a subunit of the MAP1A and MAP1B microtubule-binding proteins and plays a central role in autophagosome membrane stru...    Read more.

Monitoring Autophagy in Neurons By Christina Towers, PhD. Autophagy is a critical cellular process used by most cells in the body to recycle nutrients and prevent harmful buildup of damaged proteins. It is particularly important in the brain, where ...    Read more.

Understanding Mitophagy Mechanisms: Canonical PINK1/Parkin, LC3-Dependent Piecemeal, and LC3-Independent Mitochondrial Derived Vesicles By Christina Towers, PhD What is Mitophagy?The selective degradation of mitochondria via double membrane autophagosome vesicles is called mitophagy. Damaged mitochondria can generate harmful amounts of reactive ox...    Read more.

Read more NBR1 related blogs.