Mitofusin 2 Products

Description

MFN2 encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Bioinformatics

Entrez	170731 Mouse 64476 Rat 9927 Human
Uniprot	NM_014874 Human NP_001121132 Human NP_055689 Human O95140 Human
Product By Gene ID	9927
Alternate Names	CMT2A CMT2A2 CPRP1mitochondrial assembly regulatory factor EC 3.6.5 EC 3.6.5.- HSG KIAA0214hyperplasia suppressor MARF mitofusin 2 mitofusin-2 Transmembrane GTPase MFN2