LEDGF Products

Description

The human p75 protein is a non TAF transcription coactivator that mediates activator dependent transcription by RNA polymerase II in vitro through most tested activators. Although p75 and p52 are derived from alternatively splicing of a single gene and share most coding sequence, they reveal different function in several aspects. In addition to functioning as a transcription coactivator, p75 has been reported to be involved in regulating growth of epithelial cells, pathogenesis of atopic dermatitis and activity of HIV1 integrase.

Bioinformatics

Entrez	11168 Human
Uniprot	AAH33817 Human O75475 Human
Product By Gene ID	11168
Alternate Names	CLL-associated antigen KW-7 Dense fine speckles 70 kDa protein DFS70 LEDGFDFS 70 Lens epithelium-derived growth factor MGC74712 p52 p75 PAIP PC4 and SFRS1 interacting protein 1 PC4 and SFRS1 interacting protein 2 PC4 and SFRS1-interacting protein PSIP2 transcriptional coactivator p52/p75 Transcriptional coactivator p75/p52

Research Areas for LEDGF

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