Fc epsilon RI beta/MS4A2 Products

Description

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members. [provided by RefSeq]

Bioinformatics

Entrez	2206 Human
Uniprot	NM_000139 Human NP_000130 Human NP_000130.1 Human
Product By Gene ID	2206
Alternate Names	APY ATOPY Fc epsilon receptor I beta-chain FCER1BIGEL FCERI FcERI High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fcreceptor, beta-subunit) (Fc epsilon receptor I beta-chain) high affinity immunoglobulin epsilon receptor subunit beta IgE Fc receptor subunit beta IgE responsiveness (atopic) IGER IGHER immunoglobulin E receptor, high affinity, beta polypeptide Membrane-spanning 4-domains subfamily A member 2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, highaffinity I, receptor for; beta polypeptide) MS4A1

Research Areas for Fc epsilon RI beta/MS4A2

Find related products by research area and learn more about each of the different research areas below.

Asthma
Immunology
Signal Transduction