EIF3S3 Products

Description

Eukaryotic initiation factor 3 subunit H (eIF3H) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5'-end of cellular mRNAs near the cap structure (m7GpppN). eIF3H is a non-conserved subunit and part of the functional core of eIF3. It may function to stabilize the eIF3 complex and stimulate protein synthesis. Many cancer cell lines have been shown to express high levels of eIF3H, and it may have an oncogenic role in colorectal cancer susceptibility.

Bioinformatics

Entrez	8667 Human
Uniprot	AAH00386 Human NM_003756 Human NP_003747 Human
Product By Gene ID	8667
Alternate Names	eIF-3-gamma eIF3-gamma eIF3h eIF3-p40 EIF3S3eIF3 p40 subunit Eukaryotic translation initiation factor 3 subunit 3 eukaryotic translation initiation factor 3 subunit H eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD) eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa eukaryotic translation initiation factor 3, subunit H MGC102958

Research Areas for EIF3S3

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer