Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Goat Polyclonal
Description
DNA polymerase theta, also referred to as POLQ, is highly expressed in the testes. POLQ has a 2,590 amino acid long isoform that is approximately 290kDa and a shorter 1,786 amino acid long isoform that is approximately 198kDa. POLQ is highly expressed in the testes, plays a role in DNA polymerase activity, and may be implicated in interstrand crosslink repair (ICR). Research on DNA polymerase theta has shown a connection to several diseases and disorders including stomach cancer, malaria, breast cancer, tuberculosis, and meningioma. POLQ has also been shown to have interactions with AP2S1.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
10721 |
| Alternate Names |
- DKFZp781A0112
- DNA polymerase eta
- EC 2.7.7.7
- POLHDNA polymerase theta
- polymerase (DNA directed), theta
- PRO0327
|
Research Areas for DNA polymerase theta
Find related products by research area and learn more about each of the different research areas below.
DNA Polymerases
