Species: Hu
Applications: WB, Simple Western
Host: Goat Polyclonal
Species: Mu
Applications: WB, Simple Western
Host: Goat Polyclonal
Species: Hu
Applications: WB, CyTOF-ready, Flow
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Binding Activity
Species: Hu
Applications: PAGE, Bioactivity
Description
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).[supplied by OMIM]
Bioinformatics
Uniprot |
Human Human Human Human Human Mouse |
Product By Gene ID |
5196 |
Alternate Names |
- chemokine (C-X-C motif) ligand 4
- C-X-C motif chemokine 4
- CXCL4iroplact
- Iroplact
- MGC138298
- Oncostatin-A
- PF-4
- platelet factor 4
- SCYB4oncostatin-A
|
Research Areas for CXCL4/PF4
Find related products by research area and learn more about each of the different research areas below.
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