Species: Mu, Rt
Applications: WB, Simple Western, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB, IHC, IP, ELISA(Cap)
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, IHC, IP
Host: Rat Monoclonal
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Mu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Description
Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumour invasion and metastasis. Normally located in lysosomes of almost all mammalian cells, they can be secreted from the cell under certain conditions. Cathepsin L is responsible for most of the intralysosomal breakdown of normal cells. Cathepsin L is secreted by numerous transformed cells in its inactive proform, and mRNA expression level seems to correlate with their metastatic potential.
Bioinformatics
Entrez |
Mouse Human Rat |
Uniprot |
Human Human Human Human Human Human Mouse Human |
Product By Gene ID |
1514 |
Alternate Names |
- cathepsin L
- cathepsin L1
- CATL
- CTSLEC 3.4.22.15
- EC 3.4.22
- FLJ31037
- Major excreted protein
- MEP
|
Research Areas for Cathepsin L
Find related products by research area and learn more about each of the different research areas below.
CancerCellular Markers