BP1 Products

Description

BP1 (beta protein 1) is a homeodomain-containing isoform of DLX4. Strong BP1 expression is seen in placenta and kidney tissue, with no expression found in any other tissue.

BP1 has been shown to be activated in 80% of invasive ductal breast tumors and is associated with breast cancer progression. BP1 is also expressed in the bone marrows of 63% of acute myeloid leukemia (AML) patients. In addition, BP1 plays a role in globin gene regulation by repressing the beta-globin gene. Therefore, BP1 antibodies are useful tools for various cancer studies.

Bioinformatics

Entrez	13394 Mouse 1748 Human
Uniprot	AAH16145 Human NM_001934 Human NM_138281 Human NP_612138.1 Human Q92988 Human
Product By Gene ID	1748
Alternate Names	Beta protein 1 BP1distal-less homeo box 7 distal-less homeobox 4 DLX7distal-less homeo box 9 DLX8DLX9 homeobox protein DLX-4 Homeobox protein DLX-7 Homeobox protein DLX-8

Research Areas for BP1

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cancer
Growth and Development
Hematopoietic Stem Cell Markers
Immunology
Neuronal Cell Markers
Neuronal Stem Cell Markers
Stem Cell Markers

Related BP1 Blog Posts

Check out the latest blog posts on BP1.

BP1 Antibodies, Beta Globin and Breast Cancer: Today's post is brought to you by the letter 'B' The transcription factor beta protein 1 (BP1) is a member of the homeobox gene family and the distal-less subfamily. Expression of BP1 is highly tissue-specific and developmentally restricted. Among different human tissues, BP1 is found to be highly e...    Read more.

BRCA1 - A Critical Tumor Suppressor Gene in Women Breast cancer 1, early onset (BRCA1) is a well-known tumor suppressor gene that was originally discovered due to its link with early-onset breast and ovarian cancer in women. The BRCA1 protein contains the following domains: RING finger, RAD51-interac...    Read more.

Read more BP1 related blogs.