Alix Products

Description

Alix encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death.

Bioinformatics

Entrez	10015 Human 18571 Mouse 501083 Rat
Uniprot	AAH20066 Human AAH20066.1 Human NP_037506 Human Q8WUM4 Human
Product By Gene ID	10015
Alternate Names	AIP1DRIP4 ALG-2 interacting protein 1 ALG-2 interacting protein X ALG-2-interacting protein 1 alinx ALIX Alix apoptosis-linked gene 2-interacting protein X dopamine receptor interacting protein 4 Hp95 HP95 KIAA1375 MGC17003 PDCD6-interacting protein programmed cell death 6 interacting protein programmed cell death 6-interacting protein

Research Areas for Alix

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Apoptosis

Related Alix Blog Posts

Check out the latest blog posts on Alix.

Tools for Isolation, Quantification and Analysis of Exosomes Exosomes are spherical to cup-shaped bilayered membrane enclosed nanosize vesicles (30-100 nm) which have the ability to shuttle active cargoes between cells. Johnstone et al. 1987 pioneered in documenting the generation of exosomes in differentiat...    Read more.

Read more Alix related blogs.