Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
ALDH8A1 belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
64577 |
Alternate Names |
- Aldehyde dehydrogenase 12
- aldehyde dehydrogenase 8 family, member A1
- aldehyde dehydrogenase family protein
- ALDH12aldehyde dehydrogenase family 8 member A1
- DJ352A20.2
- DKFZp779D2315
- EC 1.2.1
- EC 1.2.1.-
- EC 1.2.1.3
- MGC138650
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