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VIPR2/VPAC2 Antibody (476031)

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VIP R2 was detected in immersion fixed paraffin-embedded sections of human brain (caudate nucleus) using 25 µg/mL Mouse Anti-Human VIP R2 Monoclonal Antibody (Catalog # MAB5416) overnight at 4 °C. Tissue was stained ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
476031
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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VIPR2/VPAC2 Antibody (476031) Summary

Immunogen
NS0 mouse myeloma cell line transfected with human VIP R2
Glu24-Ile438
Accession # P41587
Specificity
Detects human VIP R2 in direct ELISAs.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
VIPR2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 8-25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VIPR2/VPAC2 Antibody (476031)

  • FLJ16511
  • Helodermin-preferring VIP receptor
  • PACAP type III receptor
  • PACAPR3
  • PACAP-R3
  • PACAP-R-3
  • Pituitary adenylate cyclase-activating polypeptide type III receptor
  • vasoactive intestinal peptide receptor 2
  • vasoactive intestinal polypeptide receptor 2
  • VIP R2
  • VIP2R
  • VIPR2
  • VIP-R-2
  • VPAC2
  • VPCAP2R

Background

Human VIP R2 (Vasoactive intestinal polypeptide receptor 2) is a 47 kDa (predicted) seven transmembrane receptor that belongs to the G protein coupled receptor 2 family of proteins. In addition to the seven transmembrane regions, the mature chain also contains in its first extracellular region a hormone receptor domain (aa 49‑114), which includes three N-linked glycosylation sites. Human VIP R2 shares 85% aa identity with mouse and rat VIP R2. VIP R2 is expressed predominantly in skeletal muscle and to a lesser extent in the brain, heart, pancreas, and placenta. VIP R2 is coupled to a cAMP mediated signal transduction pathway and binds VIP and pituitary adenylate cyclase activating polypeptide (PACAP).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol VIPR2
Uniprot