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TREM2b Antibody (RM0139-5J46) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IHC, ICC/IF
Clone
RM0139-5J46
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 549

Order Details

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TREM2b Antibody (RM0139-5J46) [Janelia Fluor® 549] Summary

Immunogen
Mouse recombinant TREM2b (extracellular domain)
Specificity
This antibody detects mouse of TREM-2b, but not TREM-1 in Western blotting.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
TREM2
Purity
Protein A or G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TREM2b Antibody (RM0139-5J46) [Janelia Fluor® 549]

  • Trem2a
  • TREM2b
  • TREM-2b
  • Trem2c
  • TREM-2triggering receptor expressed on myeloid cells 2a
  • Triggering receptor expressed on monocytes 2
  • triggering receptor expressed on myeloid cells 2

Background

TREM2b is encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional TREM2b Products

Array NBP1-22515JF549

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Bioinformatics

Gene Symbol TREM2