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TRANCE/TNFSF11/RANK L Antibody Pair [HRP]

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Sandwich ELISA: TRANCE/TNFSF11/RANK L Antibody Pair [HRP] [NBP2-79357] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Sandwich ELISA: TRANCE/TNFSF11/RANK L Antibody Pair [HRP] [NBP2-79357] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP
Standard Curve Range
234.38-15000 pg/ml (example only; lot dependent)
Sensitivity
234.38 pg/ml (example only; lot dependent)

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
HRP
NBP2-79357-5Plates
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TRANCE/TNFSF11/RANK L Antibody Pair [HRP] Summary

Description
Solid Phase sandwich ELISA for the quantitative determination of Human TRANCE/TNFSF11/RANK L.
Additional Information
Recombinant Monoclonal Antibody
Specificity
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human TRANCE/TNFSF11/RANK L.
Standard Curve Range
234.38-15000 pg/ml (example only; lot dependent)
Sensitivity
234.38 pg/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Sample Volume
100 ul
Gene
TNFSF11

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  3. Standard

Alternate Names for TRANCE/TNFSF11/RANK L Antibody Pair [HRP]

  • CD254 antigen
  • CD254
  • ODF
  • OPGL
  • OPGLOPTB2
  • Osteoclast differentiation factor
  • Osteoprotegerin ligand
  • RANK L
  • RANKL
  • RANKLreceptor activator of nuclear factor kappa B ligand
  • Receptor activator of nuclear factor kappa-B ligand
  • sOdf
  • TNF-related activation-induced cytokine
  • TNFSF11
  • TRANCE
  • TRANCEODFhRANKL2
  • tumor necrosis factor (ligand) superfamily, member 11
  • tumor necrosis factor ligand superfamily member 11

Background

TRANCE/OPGL/RANKL/ODF is a recently identified member of tumor necrosis factor family. TRANCE (TNF-related activation-induced cytokine receptor) or RANKL {receptor activator of NF-kB (RANK) ligand} has been implicated in interactions between T cells and dendritic cells (1-2). RANK ligand (RANKL/TRANCE) binds to RANK on dendritic cells, upregulates the expression of anti-apoptotic protein BcL-XL suggesting a role in dendritic cell survival (2). TRANCE/RANKL is also important in T and B-cell maturation (3). As OPGL/ODF (Osteoprotegerin Ligand/Osteoclast differentiation factor), the same protein can both activate mature osteoclasts and mediate osteoclastogenesis (4). OPGL/TRANCE deficient mice show severe osteoporesis and complete absence of osteoclasts as a result of lack of osteogenesis (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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TRANCE/TNFSF11/RANK L ...
NBP2-79357
TRANCE/TNFSF11/RANK L Antibody Pair [HRP]
Species: Hu
Applications: ELISA

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The diverse functions of RANKL/TRANCE/TNFSF11
RANKL (also known as TNF-related activation-induced cytokine), or receptor activator of nuclear factor-?B ligand, was first discovered as a key player in the RANKL/RANK/OPG osteoclast formation pathway. Osteoclasts are large multinucleate cells t...  Read full blog post.
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Product PDFs

  SDS
  Manual - TRANCE/TNFSF11/RANK L Antibody Pair [HRP]
  PDF Datasheet
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Bioinformatics

Gene Symbol TNFSF11