TNF RII/TNFRSF1B Antibody (22221) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Tumor Necrosis Factor (TNF) is a cytokine whose function is mediated through two distinct cell surface receptors (TNF Receptor I and TNF Receptor II) that are included in the TNF receptor superfamily along with FAS antigen and CD40. TNF receptors I and II are 55 and 75 kDa members, respectively, of a family of cell surface molecules including nerve growth factor receptor, Fas/Apo1, CD30, OX40, and 4-1BB, which are characterized by cysteine rich motifs in the extracellular domain. TNF Receptor II (p75, CD120b) is present on most cell types (including monocytes, endothelial cells, Langerhans cells, and macrophages) and is considered to play a role in cell stimulation by TNF alpha. TNF Receptor II molecule is shown to be responsible for stimulation of activated T lymphocytes by TNF alpha.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array FAB226I

• TNF RII/TNFRSF1B Antibodies
• TNF RII/TNFRSF1B Antibody Pair
• TNF RII/TNFRSF1B ELISA Kits
• TNF RII/TNFRSF1B Lysate
• TNF RII/TNFRSF1B Proteins
• TNF RII/TNFRSF1B ELISAs
• TNF RII/TNFRSF1B Proteins and Enzymes