Name: TNF RII/TNFRSF1B Antibody (22210) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB726
Price: 469 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, B/N, ELISA(Cap)
Clone	22210
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Catalog# & Formulation	Size	Price
Carrier Free MAB726-SP

Carrier Free MAB726-500

Immunogen	E. coli-derived recombinant human TNF RII/TNFRSF1B Leu23-Asp257 Accession # P20333
Specificity	Detects human TNF RII in ELISAs and Western blots. In ELISAs, no cross-reactivity or interference was observed with recombinant human (rh) TNF RI, recombinant mouse (rm) TNF RI, rmTNF RII, rmTNF‑ alpha , rhTNF‑ alpha , or rhTNF‑ beta . In Western blots, this antibody does not cross‑react with rhTNF RI, rmTNF RI, or rmTNF RII.
Source	N/A
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	TNFRSF1B
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

TNF RII/TNFRSF1B Antibody (22210) [Unconjugated]

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TNF RII/TNFRSF1B Antibody (22210) [Unconjugated] Summary

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Publications for TNF RII/TNFRSF1B Antibody (MAB726)(20)

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Bioinformatics

Publications using MAB726	Applications	Species
Ben-Khemis, M;Liu, D;Pintard, C;Song, Z;Hurtado-Nedelec, M;Marie, JC;El-Benna, J;Dang, PM; TNF? counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes Redox biology 2023-09-20 [PMID: 37757542] (Neutralization, Human)	Neutralization	Human
Menevse, AN;Ammer, LM;Vollmann-Zwerenz, A;Kupczyk, M;Lorenz, J;Weidner, L;Hussein, A;Sax, J;M�hlbauer, J;Heuschneider, N;Rohrmus, C;Mai, LS;Jachnik, B;Stamova, S;Volpin, V;Durst, FC;Sorrentino, A;Xydia, M;Milenkovic, VM;Bader, S;Braun, FK;Wetzel, C;Albert, NL;Tonn, JC;Bartenstein, P;Proescholdt, M;Schmidt, NO;Linker, RA;Riemenschneider, MJ;Beckhove, P;Hau, P; TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma Acta neuropathologica communications 2023-05-08 [PMID: 37158962] (Neutralization, Human)	Neutralization	Human
B Pesce, CH Ribeiro, M Larrondo, V Ramos, L Soto, D Catalán, JC Aguillón TNF-alpha Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2 International Journal of Molecular Sciences, 2022-08-18;23(16):. 2022-08-18 [PMID: 36012570] (Neutralization, Human)	Neutralization	Human
T Baram, N Oren, N Erlichman, T Meshel, A Ben-Baruch Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFalpha Receptors in Human Triple-Negative Breast Cancer Cancers, 2022-07-19;14(14):. 2022-07-19 [PMID: 35884574] (ELISA Capture, Human)	ELISA Capture	Human
Yang Qu, Xianhao Wang, Shuai Bai, Liling Niu, Gang Zhao, Yuan Yao et al. The effects of TNF‐ alpha /TNFR2 in regulatory T cells on the microenvironment and progression of gastric cancer International Journal of Cancer 2022-04-15 [PMID: 34766338]
Dennis Kobelt, Chenyu Zhang, Isabelle Ailish Clayton-Lucey, Rainer Glauben, Cynthia Voss, Britta Siegmund et al. Pro-inflammatory TNF-alpha and IFN-gamma Promote Tumor Growth and Metastasis via Induction of MACC1 Frontiers in Immunology 5/27/2020 [PMID: 32670264]
J Sellau, M Groneberg, H Fehling, T Thye, S Hoenow, C Marggraff, M Weskamm, C Hansen, S Stanelle-B, S Kuehl, J Noll, V Wolf, NG Metwally, SH Hagen, C Dorn, J Wernecke, H Ittrich, E Tannich, T Jacobs, I Bruchhaus, M Altfeld, H Lotter Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1 Nat Commun, 2020-07-10;11(1):3459. 2020-07-10 [PMID: 32651360] (Flow Cytometry, Neutralization, Human, Mouse)	Flow Cytometry, Neutralization	Human, Mouse
W Zhu, Q Qiu, H Luo, F Zhang, J Wu, X Zhu, M Liang High Glucose Exacerbates TNF-&alpha-Induced Proliferative Inhibition in Human Periodontal Ligament Stem Cells through Upregulation and Activation of TNF Receptor 1 Stem Cells Int, 2020-02-05;2020(0):4910767. 2020-02-05 [PMID: 32089705] (Neutralization, Human)	Neutralization	Human
Q Zhou, X Wu, X Wang, Z Yu, T Pan, Z Li, X Chang, Z Jin, J Li, Z Zhu, B Liu, L Su The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-alpha/IL-33/ST2L signaling promotes gastric cancer metastasis Oncogene, 2019-10-28;0(0):. 2019-10-28 [PMID: 31659258] (Cell Culture, Human)	Cell Culture	Human
Rasheed Ahmad, Shihab Kochumon, Betty Chandy, Steve Shenouda, Merin Koshy, Amal Hasan et al. TNF-alpha Drives the CCL4 Expression in Human Monocytic Cells: Involvement of the SAPK/JNK and NF-kappa B Signaling Pathways Cellular Physiology and Biochemistry 2019-04-10 [PMID: 30964608]
H Torrey, M Khodadoust, L Tran, D Baum, A Defusco, YH Kim, DL Faustman Targeted killing of TNFR2-expressing tumor cells and Tregs by TNFR2 antagonistic antibodies in advanced Sï¿½zary syndrome Leukemia, 2018-10-24;0(0):. 2018-10-24 [PMID: 30356161] (Flow Cytometry, Human)	Flow Cytometry	Human
Linlin Wang, Dong Yang, Jing Tian, Aiqin Gao, Yihang Shen, Xia Ren et al. Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer Oncotarget 4/18/2017 [PMID: 28412748]
Christina Katanov, Shalom Lerrer, Yulia Liubomirski, Leonor Leider-Trejo, Tsipi Meshel, Jair Bar et al. Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-alpha and the NF-kappa B pathway Stem Cell Research & Therapy 2015-12-01 [PMID: 25928089]
Christopher Loosbroock, Christopher Loosbroock Inhibiting TNF-α signaling does not attenuate induction of endotoxin tolerance Journal of Inflammation Research 2014-12-16 [PMID: 25506235]
Julie A. Bastarache, Sara C. Sebag, Brandon S. Grove, Lorraine B. Ware Interferon-gamma and tumor necrosis factor-alpha act synergistically to up-regulate tissue factor in alveolar epithelial cells Experimental Lung Research 2013-04-02 [PMID: 21913843]
Zrioual S, Ecochard R, Tournadre A, Lenief V, Cazalis MA, Miossec P Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes. J. Immunol., 2009-03-01;182(0):3112-20. 2009-03-01 [PMID: 19234208] (Neutralization, Human)	Neutralization	Human
Rossol M, Meusch U, Pierer M, Kaltenhauser S, Hantzschel H, Hauschildt S, Wagner U Interaction between transmembrane TNF and TNFR1/2 mediates the activation of monocytes by contact with T cells. J. Immunol., 2007-09-15;179(6):4239-48. 2007-09-15 [PMID: 17785864] (Neutralization, Human)	Neutralization	Human
Copeland S, Siddiqui J, Remick D Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods, 2004-01-01;284(1):99-106. 2004-01-01 [PMID: 14736420] (Array Development, Human)	Array Development	Human
Jyonouchi H, Sun S, Itokazu N Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder. Neuropsychobiology, 2002-01-01;46(2):76-84. 2002-01-01 [PMID: 12378124] (ELISA Development, Human)	ELISA Development	Human
Bharucha AE, 2019, Jorgensen R, Lichtman SN, LaRusso NF, Lindor KD A pilot study of pentoxifylline for the treatment of primary sclerosing cholangitis. 2000-09-01;95(9):2338-42. 2000-09-01 [PMID: 11007239] (ELISA Development, Human)	ELISA Development	Human
Show All 20 Publications. Collapse Publications.

Gene Symbol	TNFRSF1B
Uniprot	P20333()