Recombinant Human CART Protein, CF

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Cocaine and amphetamine regulated transcript, also known as CART, is a neuropeptide protein encoded in human by the CARPT gene (1, 2) and is expressed in brain regions associated with reward such as the nucleus accumbens, also expressed in retinal cells, in pituitary glands, adrenal medulla and pancreas (3, 4). CART peptides can function as neurotransmitters and hormones, promote neuronal development, and are involved in regulating many processes, including food intake, maintenance of body weight, reward and addiction, stress response, psychostimulant effects, and endocrine function (5-7). CART production is up-regulated by CREB (8) a protein thought to be involved with the development of drug addiction, thus CART may be an important therapeutic target in the treatment of stimulant abuse (9). More recently, studies show that CART also has a wide variety of functions including bone remodeling, depression, anxiety, learning and memory as well as physiological processes such osmoregulation and blood pressure (10, 11). CART treatment promotes neuronal development and survival in vitro and in vivo (12-14).

Array 10974-CO

• CART/CARTPT Antibodies
• CART/CARTPT ELISA Kit
• CART/CARTPT Lysate
• CART/CARTPT Protein
• CART/CARTPT Proteins and Enzyme