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RCAN3 Recombinant Protein Antigen

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications AC

Order Details

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RCAN3 Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human RCAN3.

Source: E. coli

Amino Acid Sequence: ESETEEEEETKNPKQKIAQTRRPDPPTAALNEPQT

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
RCAN3
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-57619.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Theoretical MW
22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for RCAN3 Recombinant Protein Antigen

  • Down syndrome candidate region 1-like 2
  • Down syndrome critical region gene 1-like 2
  • DSCR1L2regulator of calcineurin 3 isoform 13,45,MCIP3regulator of calcineurin 3 isoform 1a2,34,5
  • hRCN3
  • Myocyte-enriched calcineurin-interacting protein 3
  • RCAN family member 3
  • RCN3
  • regulator of calcineurin 3 isoform 1a3,45,Down syndrome candidate region 1-like protein 2
  • regulator of calcineurin 3 isoform 1b2,34,5
  • regulator of calcineurin 3 isoform 1c2,34,5
  • regulator of calcineurin 3 isoform 1c3,45,calcipressin-3
  • Regulator of calcineurin 3

Background

RCAN3 (RCAN family member 3), binds to the domain of calcineurin A and inhibits calcineurin-dependent transcriptional responses. It is thought that RCAN3 may have a role in central nervous system development. Disease research is currently being studied with relation to RCAN3 and Down syndrome, chronic lymphocytic leukemia, endometrial adenocarcinoma, lymphocytic leukemia, pharyngitis, Alzheimer's Disease, and adenocarcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol RCAN3