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RanGAP1 Antibody [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-18915AF350
Alexa Fluor 405
NBP1-18915AF405
Alexa Fluor 488
NBP1-18915AF488
Alexa Fluor 532
NBP1-18915AF532
Alexa Fluor 594
NBP1-18915AF594
Alexa Fluor 647
NBP1-18915AF647
Alexa Fluor 700
NBP1-18915AF700
Alexa Fluor 750
NBP1-18915AF750
Biotin
NBP1-18915B
CoraFluor 1
NBP1-18915CL1
DyLight 350
NBP1-18915UV
DyLight 488
NBP1-18915G
DyLight 550
NBP1-18915R
DyLight 594
NBP1-18915DL594
DyLight 650
NBP1-18915C
DyLight 680
NBP1-18915FR
DyLight 755
NBP1-18915IR
FITC
NBP1-18915F
HRP
NBP1-18915H
Janelia Fluor 525
NBP1-18915JF525
Janelia Fluor 549
NBP1-18915JF549
Janelia Fluor 646
NBP1-18915JF646
Janelia Fluor 669
NBP1-18915JF669
Unconjugated
NBP1-18915
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RanGAP1 Antibody [DyLight 405] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human Ran GTPase activating protein 1 using the numbering given in entry NP_002874.1 (GeneID 5905).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RANGAP1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for RanGAP1 Antibody [DyLight 405]

  • Fug1
  • KIAA1835Fug1
  • MGC20266
  • Ran GTPase activating protein 1
  • ran GTPase-activating protein 1
  • RanGAP1
  • SD
  • segregation distorter homolog (Drosophila)
  • segregation distorter homolog
  • segregation distortion

Background

RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RANGAP1