PU.1/Spi-1 Antibody

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using NBP1-00135	Applications	Species
Uvarov P, Ludwig A, Markkanen M et al. Upregulation of the neuron-specific K+/Cl- cotransporter expression by transcription factor early growth response 4. J Neurosci 2006-12-27 [PMID: 17192429]
Harendza S, Lovett DH, Stahl RA et al. The hematopoietic transcription factor PU.1 represses gelatinase A transcription in glomerular mesangial cells. J Biol Chem 2000-06-01 [PMID: 10867017]

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	Flow	Human	10/16/2014	View Summary Application Flow Cytometry Sample Tested Control 293T cell and cells transfected with p3XFLAG-PU.1 Species Human
Enlarge	3 reviewed by: Verified Customer	WB	Human	10/16/2014	View Summary Application Western Blot Sample Tested 293T lysate Species Human

Array NBP1-00135

• PU.1/Spi-1 Antibodies
• PU.1/Spi-1 Lysates
• PU.1/Spi-1 Proteins