PPAP2C Antibody

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Western Blot: PPAP2C Antibody [NBP3-11903] - Western blot analysis using PPAP2C antibody on vector-controlled HEK-293 cells (V) and HEK-293 cells overexpressing LPP2 protein (2) at 1 ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

PPAP2C Antibody Summary

Immunogen
Unique peptide derived from the human lysophospholipid phosphatase 2 protein. (Uniprot: O43688)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PLPP2
Purity
Ammonium sulfate precipitation
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Applications/Dilutions

Dilutions
  • Western Blot 10 - 15 ug/ml
Application Notes
This antibody can be used for Western blotting (10-15 ug/ml). NOTE: Boiling LPP2 with sample buffer will aggregate the protein. Lysates should be prepared by mixing cells with lysis buffer (possibly with extra detergent) to solubilize the protein before adding sample buffer and lysate SHOULD NOT be boiled/heated..

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.08% Sodium Azide
Purity
Ammonium sulfate precipitation

Alternate Names for PPAP2C Antibody

  • EC 3.1.3.4
  • LPP2PAP2-g
  • PAP2c
  • PAP-2clipid phosphate phosphohydrolase 2
  • PAP2-G
  • PAP2-gamma
  • Phosphatidate phosphohydrolase type 2c
  • Phosphatidic acid phosphatase 2c
  • phosphatidic acid phosphatase type 2C
  • phosphatidic acid phosphohydrolase type 2c
  • type-2 phosphatidic acid phosphatase-gamma

Background

PPAP2C, also referred to as Phosphatidic Acid Phosphatase Type 2C, has a canonical sequence that is 288 amino acids long and approximately 32kDa, and two other isoforms that are 309 and 232 amino acids in length, respectively. PPAP2C is an enzyme that hydrolyzes S1P, C1P and LPA, and catalyzes the conversion of phosphatidic acid to diacylglycerol. Current research surrounding PPAP2C has shown a possible linkage with strabismus and gastroenteritis. PPAP2C has also been shown to interact with APLP1, BAG6, GALC, MLH1, and UNC119 in pathways such as triacylglyceride synthesis, sphingolipid metabolism, triacylglycerol biosynthesis, and Fc gamma R-mediated phagocytosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PLPP2
Uniprot