PLS1 Antibody (3G10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. Fimbrin is a 68-kD actin-bundling protein. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using H00005357-M04	Applications	Species
Morandell J, Schwarz LA, Basilico B et al. Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development Nature Communications 2021-05-24 [PMID: 34031387]
Krey JF, Krystofiak ES, Dumont RA et al. Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid. J Cell Biol 2016-11-21 [PMID: 27811163]

Array H00005357-M04

• PLS1 Antibodies
• PLS1 ELISA Kits
• PLS1 Lysate
• PLS1 Proteins