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Oval Cell Marker Antibody (OC2-4E8) [DyLight 755]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, ICC/IF, IHC
Clone
OC2-4E8
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 755

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Oval Cell Marker Antibody (OC2-4E8) [DyLight 755] Summary

Description
This product is provided as conjugated tissue culture supernatant. Due to the crude preparation of the antibody material, excess dye may remain in the final product. We highly recommend taking necessary precautions, such as adding additional wash steps and running proper controls.
Immunogen
Nonparenchymal cells from DDC-treated mice to induce the oval cell response.
Localization
Cell surface
Marker
Hepatic periductal cell Marker
Specificity
Specific for both proliferating and normal hepatic periductal cells.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Tissue culture supernatant

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Background

Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts (1). To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Oval Cell Marker Products

Array NBP1-18971IR

Research Areas for Oval Cell Marker Antibody (NBP1-18971IR)

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Calculators

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