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MTA2 Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76748AF350
Alexa Fluor 405
NBP1-76748AF405
Alexa Fluor 488
NBP1-76748AF488
Alexa Fluor 532
NBP1-76748AF532
Alexa Fluor 594
NBP1-76748AF594
Alexa Fluor 647
NBP1-76748AF647
Alexa Fluor 700
NBP1-76748AF700
Alexa Fluor 750
NBP1-76748AF750
Biotin
NBP1-76748B
CoraFluor 1
NBP1-76748CL1
DyLight 350
NBP1-76748UV
DyLight 405
NBP1-76748V
DyLight 488
NBP1-76748G
DyLight 594
NBP1-76748DL594
DyLight 650
NBP1-76748C
DyLight 680
NBP1-76748FR
DyLight 755
NBP1-76748IR
FITC
NBP1-76748F
HRP
NBP1-76748H
Janelia Fluor 525
NBP1-76748JF525
Janelia Fluor 549
NBP1-76748JF549
Janelia Fluor 646
NBP1-76748JF646
Janelia Fluor 669
NBP1-76748JF669
PerCP
NBP1-76748PCP
Unconjugated
NBP1-76748
mFluor Violet 450 SE
NBP1-76748MFV450
mFluor Violet 500 SE
NBP1-76748MFV500
mFluor Violet 610 SE
NBP1-76748MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-76748
BSA Free
NBP1-76748
BSA Free
NBP1-76748-0.025mg
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MTA2 Antibody [DyLight 550] Summary

Immunogen
Antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PID. The immunogen is located within the last 50 amino acids of PID. Amino Acid Squence: PAPSHPASTNEPIVLED
Specificity
PID antibody is predicted to not cross-react with MTA2
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MTA2
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MTA2 Antibody [DyLight 550]

  • DKFZp686F2281
  • metastasis associated 1 family, member 2
  • metastasis -associated gene 1-like 1
  • metastasis associated gene family, member 2
  • Metastasis-associated 1-like 1
  • metastasis-associated protein 2
  • metastasis-associated protein MTA2
  • MTA1-L1 protein
  • MTA1L1MTA1-L1
  • p53 target protein in deacetylase complex
  • PID

Background

Official Gene Symbol: MTA2 Gen Bank Accession Number: NP_004730 Gene ID: 9219 (Human) Gene Map Locus: 11q12-q13.1 (human) MTA2, a homologue of human MTA1 and MTA3, is a member of highly conserved MTA gene family. It is a component of NuRD, an ATP-dependent nucleosome remodeling and histone deacetylase complex. MTA2 is a nuclear protein that interacts with HDAC1 and HDAC2 and has a functional role in chromatin remodeling and deacetylase activity. MTA2 specifically interacts with p53 and represses p53-dependant transcriptional activation, thereby regulating p53-mediated cell growth arrest and apoptosis. It also inhibits the transcriptional activity of Estrogen receptor-alpha. Northern Blot analysis detected a ubiquitous expression of MTA2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MTA2