Name: Human IL-12 p70 DuoSet ELISA, 15 Plate
Brand: Novus Biologicals
SKU: DY1270
Price: 435 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	ELISA
Conjugate	Biotin

Source	N/A
Assay Type	Solid Phase Sandwich ELISA
Inter-Assay	See PDF Datasheet for details
Intra-Assay	See PDF Datasheet for details
Spike Recovery	See PDF Datasheet for details
Sample Volume	See PDF Datasheet for details
Gene	IL12A

Publications using DY1270	Applications	Species
Kalkusova, K;Taborska, P;Stakheev, D;Rataj, M;Smite, S;Darras, E;Albo, J;Bartunkova, J;Vannucci, L;Smrz, D; Impaired Proliferation of CD8+ T Cells Stimulated with Monocyte-Derived Dendritic Cells Previously Matured with Thapsigargin-Stimulated LAD2 Human Mast Cells Journal of immunology research 2024-07-18 [PMID: 39056014] (Human)		Human
Katsoulis, O;Toussaint, M;Jackson, MM;Mallia, P;Footitt, J;Mincham, KT;Meyer, GFM;Kebadze, T;Gilmour, A;Long, M;Aswani, AD;Snelgrove, RJ;Johnston, SL;Chalmers, JD;Singanayagam, A; Neutrophil extracellular traps promote immunopathogenesis of virus-induced COPD exacerbations Nature communications 2024-07-09 [PMID: 38982052] (Human)		Human
Twarog, M;Schustak, J;Xu, Y;Coble, M;Dolan, K;Esterberg, R;Huang, Q;Saint-Geniez, M;Bao, Y; TNF? induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function Scientific reports 2023-09-02 [PMID: 37660150] (Human)		Human
M Jovanovic, S Sekulic, M Jocic, M Jurisevic, N Gajovic, M Jovanovic, N Arsenijevi, M Jovanovic, M Mijailovic, M Milosavlje, I Jovanovic Increased Pro Th1 And Th17 Transcriptional Activity In Patients With Severe COVID-19 International Journal of Medical Sciences, 2023-02-21;20(4):530-541. 2023-02-21 [PMID: 37057213] (Human)		Human
D Tortolani, C Di Meo, S Standoli, F Ciaramella, S Kadhim, E Hsu, C Rapino, M Maccarrone Rare Phytocannabinoids Exert Anti-Inflammatory Effects on Human Keratinocytes via the Endocannabinoid System and MAPK Signaling Pathway International Journal of Molecular Sciences, 2023-02-01;24(3):. 2023-02-01 [PMID: 36769042] (Human)		Human
D Kabelitz, M Zarobkiewi, M Heib, R Serrano, M Kunz, G Chitadze, D Adam, C Peters Signal strength of STING activation determines cytokine plasticity and cell death in human monocytes Scientific Reports, 2022-10-24;12(1):17827. 2022-10-24 [PMID: 36280676] (Human)		Human
A Rosewell S, C Porter, G Biegert, L Jatta, M Suzuki HydrAd: A Helper-Dependent Adenovirus Targeting Multiple Immune Pathways for Cancer Immunotherapy Oncogene, 2022-06-02;14(11):. 2022-06-02 [PMID: 35681750] (Human)		Human
L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma Cells, 2022-04-30;11(9):. 2022-04-30 [PMID: 35563820] (Human)		Human
A Laustsen, RM van der Sl, A Gris-Olive, SS Hernández, E Cemalovic, HQ Tang, LH Pedersen, N Uldbjerg, MR Jakobsen, RO Bak Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells Elife, 2021-09-02;10(0):. 2021-09-02 [PMID: 34473049] (Human)		Human
RP Madeira, LM Dal'Mas Ro, P de Cássia, C Mady, BM Ianni, AC Torrecilha New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response Journal of Immunology Research, 2021-01-11;2021(0):6650670. 2021-01-11 [PMID: 33506056] (Human)		Human
SK Biswas, M Mittal, E Sinha, V Singh, N Arela, B Bajaj, PK Tiwari, VM Katoch, KK Mohanty Exploring the Role of C-C Motif Chemokine Ligand-2 Single Nucleotide Polymorphism in Pulmonary Tuberculosis: A Genetic Association Study from North India Journal of Immunology Research, 2020-12-16;2020(0):1019639. 2020-12-16 [PMID: 33381602] (Human)		Human
M De, A Bhushan, S Chinnaswam Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-&lambda3 or IFN-&lambda4 show distinct phenotypes J Leukoc Biol, 2020-11-17;0(0):. 2020-11-17 [PMID: 33205487] (Human)		Human
ME Morrissey, R Byrne, C Nulty, NH McCabe, N Lynam-Lenn, CT Butler, S Kennedy, D O'Toole, J Larkin, P McCormick, B Mehigan, MC Cathcart, J Lysaght, JV Reynolds, EJ Ryan, MR Dunne, J O'Sullivan The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation BMC Cancer, 2020-06-17;20(1):566. 2020-06-17 [PMID: 32552799] (Human)		Human
Z Mohamed Am, MA Che Ani, SW Tan, SK Yeap, NB Alitheen, SUF Syed Najmu, J Kalyanasun, SC Chan, A Veerakumar, SL Chia, K Yusoff Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer Sci Rep, 2019-09-30;9(1):13999. 2019-09-30 [PMID: 31570732] (Chicken, Human)		Chicken, Human
M Pascual-Ga, E Bonfill-Te, E Planas-Rig, C Rubio-Pere, R Iurlaro, A Arias, I Cuartas, A Sala-Hojma, L Escudero, F Martínez-R, I Huber-Ruan, P Nuciforo, L Pedrosa, C Marques, I Braña, E Garralda, M Vieito, M Squatrito, E Pineda, F Graus, C Espejo, J Sahuquillo, J Tabernero, J Seoane LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy Nat Commun, 2019-06-11;10(1):2416. 2019-06-11 [PMID: 31186412] (Human)		Human
R Gramlich, E Aliahmadi, M Peiser In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists Int J Mol Sci, 2019-03-19;20(6):. 2019-03-19 [PMID: 30893757] (Human)		Human
I Ugele, ZE Cárdenas-C, K Hammon, M Wehrstein, C Bruss, K Peter, K Singer, E Gottfried, J Boesch, P Oefner, K Dettmer, K Renner, M Kreutz D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells Int J Mol Sci, 2019-02-10;20(3):. 2019-02-10 [PMID: 30744183] (Human)		Human
B Walch-Rück, R Ströder, L Theobald, J Pahne-Zepp, S Hegde, YJ Kim, RM Bohle, I Juhasz-Bös, EF Solomayer, S Smola Cervical cancer-instructed stromal fibroblasts enhance IL-23 expression in dendritic cells to support expansion of Th17 cells Cancer Res., 2019-01-29;0(0):. 2019-01-29 [PMID: 30696656] (Human)		Human
AO Idowu, S Bhattachar, S Gradus, W Oyibo, Z George, C Black, J Igietseme, AA Azenabor Plasmodium falciparum Treated with Artemisinin-based Combined Therapy Exhibits Enhanced Mutation, Heightened Cortisol and TNF-? Induction Int J Med Sci, 2018-09-07;15(13):1449-1457. 2018-09-07 [PMID: 30443164] (Human)		Human
A Laustsen, RO Bak, C Krapp, L Kjær, JH Egedahl, CC Petersen, S Pillai, HQ Tang, N Uldbjerg, M Porteus, NR Roan, M Nyegaard, PW Denton, MR Jakobsen Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function Nat Commun, 2018-08-30;9(1):3525. 2018-08-30 [PMID: 30166549] (Human)		Human
T Nakajima, H Yoshifuji, M Shimizu, K Kitagori, K Murakami, R Nakashima, Y Imura, M Tanaka, K Ohmura, F Matsuda, C Terao, T Mimori A novel susceptibility locus in the IL12B region is associated with the pathophysiology of Takayasu arteritis through IL-12p40 and IL-12p70 production Arthritis Res. Ther., 2017-09-06;19(1):197. 2017-09-06 [PMID: 28874185] (Human)		Human
A Mangas-Los, R García-Gar, A Urios, D Escudero-G, J Tosca, R Giner-Durá, MA Serra, C Montoliu, V Felipo Minimal hepatic encephalopathy is associated with expansion and activation of CD(4+)CD28(-), Th22 and Tfh and B lymphocytes Sci Rep, 2017-07-27;7(1):6683. 2017-07-27 [PMID: 28751644] (Human)		Human
Philipp Kotthoff, Annkristin Heine, Stefanie Andrea Erika Held, Peter Brossart Dexamethasone induced inhibition of Dectin-1 activation of antigen presenting cells is mediated via STAT-3 and NF-?B signaling pathways. Scientific Reports, 2017-07-03;0(0):2045-2322. 2017-07-03 [PMID: 28674449] (Human)		Human
YA Hayman, LR Sadofsky, JD Williamson, SP Hart, AH Morice The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration? ERJ Open Res, 2017-03-20;3(1):. 2017-03-20 [PMID: 28344981] (Human)		Human
RP Timoteo, MV da Silva, CB Miguel, DA Silva, JD Catarino, V Rodrigues, H Sales-Camp, CJ Freire Oli Th1/Th17-Related Cytokines and Chemokines and Their Implications in the Pathogenesis of Pemphigus Vulgaris Mediators Inflamm., 2017-02-22;2017(0):7151285. 2017-02-22 [PMID: 28321152] (Human)		Human
Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages Infect Immun, 2016-09-19;0(0):. 2016-09-19 [PMID: 27481240] (Human)		Human
Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype Sci Rep, 2016-07-19;6(0):29712. 2016-07-19 [PMID: 27431276] (Human)		Human
Chene A, d'Almeida S, Blondy T, Tabiasco J, Deshayes S, Fonteneau J, Cellerin L, Delneste Y, Gregoire M, Blanquart C Pleural Effusions from Patients with Mesothelioma Induce Recruitment of Monocytes and Their Differentiation into M2 Macrophages. J Thorac Oncol, 2016-07-12;11(10):1765-73. 2016-07-12 [PMID: 27418105] (Human)		Human
Mattiola I, Pesant M, Tentorio P, Molgora M, Marcenaro E, Lugli E, Locati M, Mavilio D Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1beta, IFN-beta, and IL-15 Pathways. J Immunol, 2015-08-14;195(6):2818-28. 2015-08-14 [PMID: 26276870] (Human)		Human
Fernandes R, Bachiega T, Rodrigues D, Golim M, Dias-Melicio L, Balderramas H, Kaneno R, Soares A Paracoccidioides brasiliensis interferes on dendritic cells maturation by inhibiting PGE2 production. PLoS ONE, 2015-03-20;10(3):e0120948. 2015-03-20 [PMID: 25793979] (Human)		Human
Jaguin M, Fardel O, Lecureur V Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2. PLoS ONE, 2015-02-24;10(2):e0116560. 2015-02-24 [PMID: 25710172] (Human)		Human
Wu J, Hsu H, Chiu Y, Chen H, Ni Y, Chang M The effects of cytokines on spontaneous hepatitis B surface antigen seroconversion in chronic hepatitis B virus infection. J Immunol, 2014-12-12;194(2):690-6. 2014-12-12 [PMID: 25505294] (Human)		Human
Tudor C, Bruns H, Daniel C, Distel L, Hartmann A, Gerbitz A, Buettner M Macrophages and dendritic cells as actors in the immune reaction of classical Hodgkin lymphoma. PLoS ONE, 2014-12-03;9(12):e114345. 2014-12-03 [PMID: 25470820] (Human)		Human
Wang L, Deng Q, Wang J, Bai X, Xiao X, Lv H, Zhao M, Liu P Effect of CIK on multidrug-resistance reversal and increasing the sensitivity of ADR in K562/ADR cells. Oncol Lett, 2014-07-10;8(4):1778-1782. 2014-07-10 [PMID: 25202409] (Human)		Human
O'Toole A, Michielsen A, Nolan B, Tosetto M, Sheahan K, Mulcahy H, Winter D, Hyland J, O'Connell P, Fennelly D, O'Donoghue D, O'Sullivan J, Doherty G, Ryan E Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive. Br J Cancer, 2014-07-24;111(5):927-32. 2014-07-24 [PMID: 25058349] (Human)		Human
Zhang Y, Chen H, Sun C, Wang H, Liu M, Li Y, Nie X, Du M, Li D, Zhang J Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy. PLoS ONE, 2014-06-16;9(6):e99612. 2014-06-16 [PMID: 24932916] (Human)		Human
Tanaka K, Ohgo Y, Katayanagi Y, Yasui K, Hiramoto S, Ikemoto H, Nakata Y, Miyoshi N, Isemura M, Ohashi N, Imai S Anti-inflammatory effects of green soybean extract irradiated with visible light. Sci Rep, 2014-04-22;4(0):4732. 2014-04-22 [PMID: 24751752] (Human)		Human
Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells. Br J Haematol, 2014-01-15;165(1):134-44. 2014-01-15 [PMID: 24428589] (Human)		Human
Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G, Bardessono M, Pasquali C, Mantovani A, Sozzani S, Bosisio D Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway. PLoS ONE, 2013-12-30;8(12):e82867. 2013-12-30 [PMID: 24386121] (Human)		Human
Giordani L, Del Pinto T, Vincentini O, Felli C, Silano M, Viora M Two wheat decapeptides prevent gliadin-dependent maturation of human dendritic cells. Exp Cell Res, 2013-11-19;321(2):248-54. 2013-11-19 [PMID: 24262078] (Human)		Human
Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, Pierroz D, Morandi L, De Simone M, Rucci N, Bertini E, Bianchi ML, De Benedetti F, Teti A Mechanisms inducing low bone density in duchenne muscular dystrophy in mice and humans. J. Bone Miner. Res., 2011-08-01;26(8):1891-903. 2011-08-01 [PMID: 21509823] (Human)		Human
Ochiel DO, Ghosh M, Fahey JV Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands. J. Leukoc. Biol., 2010-04-12;88(3):435-44. 2010-04-12 [PMID: 20385795] (Human)		Human
Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Batmunkh R, Rentsenhand B, Makino H, Ranjan P, Minakuchi K, Sone S Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property. J. Immunol., 2009-12-15;183(12):8176-85. 2009-12-15 [PMID: 20007583] (Human)		Human
Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 2009-03-02;119(10):1424-32. 2009-03-02 [PMID: 19255340] (Human)		Human
Alvarado-Navarro A, Montoya-Buelna M, Munoz-Valle JF, Lopez-Roa RI, Guillen-Vargas C, Fafutis-Morris M The 3'UTR 1188 A/C polymorphism in the interleukin-12p40 gene (IL-12B) is associated with lepromatous leprosy in the west of Mexico. Immunol. Lett., 2008-04-28;118(2):148-51. 2008-04-28 [PMID: 18485489] (Human)		Human
Spadaro M, Caorsi C, Ceruti P, Varadhachary A, Forni G, Pericle F, Giovarelli M Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells. FASEB J., 2008-03-25;22(8):2747-57. 2008-03-25 [PMID: 18364398] (Human)		Human
Matalka KZ, Ali D, Khawad AE, Qa'dan F The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation. Cytokine, 2007-11-26;40(3):235-40. 2007-11-26 [PMID: 18036829] (Human)		Human
Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J. Clin. Invest., 2007-12-01;117(12):3664-3672. 2007-12-01 [PMID: 17992260] (Human)		Human
Duluc D, Delneste Y, Tan F, Moles MP, Grimaud L, Lenoir J, Preisser L, Anegon I, Catala L, Ifrah N, Descamps P, Gamelin E, Gascan H, Hebbar M, Jeannin P Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Blood, 2007-09-11;110(13):4319-30. 2007-09-11 [PMID: 17848619] (Human)		Human
Lauzon NM, Mian F, MacKenzie R, Ashkar AA The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Cell. Immunol., 2006-10-17;241(2):102-12. 2006-10-17 [PMID: 17049504] (Human)		Human
Macagno A, Molteni M, Rinaldi A A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. J. Exp. Med., 2006-05-22;203(6):1481-92. 2006-05-22 [PMID: 16717116] (Human)		Human
Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur. J. Immunol., 2005-08-01;35(8):2459-70. 2005-08-01 [PMID: 16021602] (Human)		Human
Weigt H, Muhlradt PF, Larbig M, Krug N, Braun A The Toll-like receptor-2/6 agonist macrophage-activating lipopeptide-2 cooperates with IFN-gamma to reverse the Th2 skew in an in vitro allergy model. J. Immunol., 2004-05-15;172(10):6080-6. 2004-05-15 [PMID: 15128792] (Human)		Human
Asselin-Paturel C, Brizard G, Pin JJ, Briere F, Trinchieri G Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J. Immunol., 2003-12-15;171(12):6466-77. 2003-12-15 [PMID: 14662846] (Mouse)		Mouse
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Human IL-12 p70 DuoSet ELISA, 15 Plate

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