HLA DQA2 Antibody

The HLA-DQA2 gene encodes a 255 amino acid long, 28 kDA HLA class II histocompatibility antigen, DQ alpha 2 chain that functions in the peptide loading of MHC class II molecules. It does so by releasing the CLIP molecule from the peptide binding site. The HLA-DQA2 gene participates in cell adhesion molecules (CAMs), antigen processing and presentation, transport of MHC II:Ii complex along Golgi to TGN, the CDC42 pathway, and in G-protein signaling in N-RAS regulation pathways. It is known to interact with genes CD4 and HLA-DQB1. HLA-DQA2 is linked to osteoarthritis, celiac disease, diabetes, asthma, thyroiditis, childhood type dermatomyositis, graft vs. host disease, narcolepsy, and lupus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP1-52094	Applications	Species
Davila S, Froeling FE, Tan A et al. New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun 2010-04-01 [PMID: 20237496]

Array NBP1-52094

• HLA DQA2 Antibodies
• HLA DQA2 Lysate