HIV-1 gp120 Antibody [Alexa Fluor® 647] Summary
Immunogen |
Antibody was raised against 16 amino acid synthetic peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop. The immunogen is located within amino acids 80 - 130 of gp120. Amino Acid Squence: EQMHEDIISLWDQLSK |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
env |
Purity |
Peptide affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Reactivity Notes
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Peptide affinity purified |
Notes
Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for HIV-1 gp120 Antibody [Alexa Fluor® 647]
Background
HIV-1 gp120 is a surface glycoprotein that enables viral attachment and entry into host cells. It is also involved in neurotoxicity and has been implicated in HIV-associated neurocognitive disorders. HIV-1 gp120 also induces apoptosis in neuronal cells by signaling mitochondrial-death proteins which may upregulate the death receptor, Fas. Because HIV gp120 is necessary for HIV-1 to enter CD4 cells, gp120 is one of the main targets of HIV vaccine research.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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