Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
The endothelium is the layer of thin specialized epithelium, comprising a simple squamous layer of cells that line the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall (simple squamous epithelium). Endothelial cells line the entire circulatory system, from the heart to the smallest capillary. Endothelial cells are involved in many aspects of vascular biology, such as vasoconstriction and vasodilation, and hence the control of blood pressure; blood clotting (thrombosis & fibrinolysis); atherosclerosis; formation of new blood vessels (angiogenesis) and inflammation and swelling (oedema). Endothelial cells also control the passage of materials, and the transit of white blood cells, into and out of the bloodstream.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Publications for Hepatic Sinusoidal Endothelial Cells Antibody (NB110-68095AF488)(1)
We have publications tested in 1 confirmed species: Human.
We have publications tested in 1 application: IF/IHC.
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![Flow Cytometry: Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [Alexa Fluor® 488] [NB110-68095AF488] - Representative sequential gating during flow cytometry analysis of rat non-parenchymal liver cells (n = 4). Cells were labeled with antibodies to SE-1 (NB110-68095AF488), CD31, and CD45 (NB100-64895PE). LSECs were then identified as SE-1-Alexa488+ cells (e), and the biexponential CD45-PE/CD31-APC of events (f) were used to display and select the CD45+ CD31+ subsets of LSECs. FMOs (used for gating), and single antibody staining controls are shown in Additional file. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/33246411/) licensed under a CC-BY license.](http://images.novusbio.com/fullsize/Hepatic-Sinusoidal-Endothelial-Cells-Antibody-SE-1-Alexa-Fluor-R-488-Flow-Cytometry-NB110-68095AF488-img0001.jpg "Flow Cytometry: Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [Alexa Fluor® 488] [NB110-68095AF488] - Representative sequential gating during flow cytometry analysis of rat non-parenchymal liver cells (n = 4). Cells were labeled with antibodies to SE-1 (NB110-68095AF488), CD31, and CD45 (NB100-64895PE). LSECs were then identified as SE-1-Alexa488+ cells (e), and the biexponential CD45-PE/CD31-APC of events (f) were used to display and select the CD45+ CD31+ subsets of LSECs. FMOs (used for gating), and single antibody staining controls are shown in Additional file. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/33246411/) licensed under a CC-BY license.")
![Immunocytochemistry/ Immunofluorescence: Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [Alexa Fluor® 488] [NB110-68095AF488] - Immune histochemistry of acetone-fixed frozen rat liver sections. The sections were double immune-labeled with primary antibodies against a-b) stabilin-2 (STAB2; green fluorescence), & Fc gamma RIIb2 (SE-1; red fluorescence), or against c) stabilin-2 (STAB2; green fluorescence), & CD11b/c (red fluorescence). Antibodies are listed in Table 1. Pv, portal vein. Nuclei were stained with DAPI (blue fluorescence in overlay images) Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/33246411), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb110-68095af488_mouse-monoclonal-hepatic-sinusoidal-endothelial-cells-antibody-se-1-alexa-fluor-488-310202415392513.jpg "Immunocytochemistry/ Immunofluorescence: Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [Alexa Fluor® 488] [NB110-68095AF488] - Immune histochemistry of acetone-fixed frozen rat liver sections. The sections were double immune-labeled with primary antibodies against a-b) stabilin-2 (STAB2; green fluorescence), & Fc gamma RIIb2 (SE-1; red fluorescence), or against c) stabilin-2 (STAB2; green fluorescence), & CD11b/c (red fluorescence). Antibodies are listed in Table 1. Pv, portal vein. Nuclei were stained with DAPI (blue fluorescence in overlay images) Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/33246411), licensed under a CC-BY license. Not internally tested by Novus Biologicals.")
![Flow Cytometry: Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [FITC] [NB110-68095F] - Flow Cytometry: Surface staining of Rat Liver sinusoidal endothelial cells with Mouse anti-Rat Hepatic Sinusoidal Endothelial Cells [FITC] [NB110-68095F] and negative control. Total viable cells were used for analysis. Image courtesy of customer.](https://images.novusbio.com/images/Hepatic-Sinusoidal-Endothelial-Cells-Antibody-SE-1-FITC-Flow-Cytometry-NB110-68095F-img0001.jpg "Flow Cytometry: Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [FITC] [NB110-68095F] - Flow Cytometry: Surface staining of Rat Liver sinusoidal endothelial cells with Mouse anti-Rat Hepatic Sinusoidal Endothelial Cells [FITC] [NB110-68095F] and negative control. Total viable cells were used for analysis. Image courtesy of customer.")