GSTM3 Antibody (20C11.H5.E11) [DyLight 488]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, IHC, IP, PAGE
Clone
20C11.H5.E11
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

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GSTM3 Antibody (20C11.H5.E11) [DyLight 488] Summary

Immunogen
This Protein A purified GSTM3 Antibody (20C11.H5.E11) was prepared by repeated immunizations in mice with GSTGSTM3 Protein (Uniprot: P21266)
Specificity
Reacts specifically with GSTM3 protein.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GSTM3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunoprecipitation
  • SDS-Page
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Cross reactivity from other sources has not been determined

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GSTM3 Antibody (20C11.H5.E11) [DyLight 488]

  • glutathione S-transferase mu 3 (brain)
  • GST5Mu-3
  • MGC3310
  • MGC3704
  • S-(hydroxyalkyl)glutathione lyase M3

Background

GSTM3, also known as Glutathione S-transferase Mu 3, is a 225 amino acid that is approx. 27 kDa; is responsible for conjugation of reduced glutathione to an extensive number of exogenous and endogenous hydrophobic electrophiles, and may be able to regulate uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers. Current research is being performed on over 70 diseases and disorders including laryngeal squamous cell carcinoma, pharyngitis, laryngitis, squamous cell carcinoma, laryngeal cancer, oral cancer, cataract, colorectal cancer, carcinoma, breast cancer, astrocytoma, non-Hodgkin lymphoma, malignant pleural mesothelioma, open-angle glaucoma, Hodgkin's lymphoma, lung cancer, basal cell carcinoma, adult brain tumor, and leukoplakia. This protein has been shown to have interactions with over 70 proteins including RBL2, GSTM2, PAK2, MPG, and TFE3 in pathways such as glutathione metabolism, metabolism of xenobiotics by cytochrome P450, drug metabolism - cytochrome P450, establishment of blood-nerve barrier, and response to estrogen stimulus pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GSTM3