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GHRH Antibody (C2)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
C2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

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GHRH Antibody (C2) Summary

Immunogen
Immunized with recombinant Human GHRH (Uniprot#: P01286; Cys19-Gly108 (Uniprot#: P01286)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GHRH
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-40ug/mL
  • Western Blot 0.01-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for GHRH Antibody (C2)

  • GHRFsomatocrinin
  • GRF
  • growth hormone releasing hormone
  • Growth hormone-releasing factor
  • Growth hormone-releasing hormone
  • INN
  • MGC119781
  • sermorelin
  • Somatocrinin
  • somatoliberin
  • somatorelin

Background

GHRH, also known as Somatoliberin or Growth hormone-releasing hormone, has a 108 amino acid isoform and a 107 amino acid isoform that are 12 kDa, is produced by the hypothalamus and its main function is to stimulate growth hormone release. Disease research is being performed on this proteins involvement in gigantism, isolated growth hormone deficiency due to defect in ghrf, dwarfism, gigantism due to ghrf hypersecretion, zollinger-ellison syndrome, anorexia, nervosa, multiple endocrine neoplasia, polycystic ovary syndrome, short stature, Cushing's syndrome, hypopituitarism, diabetes insipidus, panic disorder, hypothyroidism, somatostatinoma, acromegaly, vipoma, pituitary adenoma, Prader-Willi syndrome, hyperprolactinemia, cancer, lipodystrophy, hypogonadism, diabetes mellitus, and Pseudohypoparathyroidism. This protein has been involved in 55 different pathways such as nuclear receptor activation by vitamin-A, Paxillin Interactions, telomerase components in cell signaling, mitochondrial apoptosis, molecular mechanisms of cancer, antioxidant action of vitamin-C, eIF2 pathway, intracellular calcium signaling, JNK pathway, apoptotic pathways in synovial fibroblasts, ERK5 signaling, Tec kinases signaling, GSK3 signaling, and cellular apoptosis pathway where it interacts with GHRHR, DPP4, FAP, ADCYAP1R1, POMC, NPS, MC4R, ADRB1, and 50 other proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for GHRH Antibody (NBP3-41494) (0)

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Secondary Antibodies

 

Isotype Controls

Additional GHRH Products

Array NBP3-41494

Research Areas for GHRH Antibody (NBP3-41494)

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Bioinformatics

Gene Symbol GHRH