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GGCX Antibody [Janelia Fluor® 635]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 635

Order Details

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GGCX Antibody [Janelia Fluor® 635] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human GGCX fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GGCX
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for GGCX Antibody [Janelia Fluor® 635]

  • EC 4.1.1.90
  • gamma-glutamyl carboxylaseFLJ26629
  • GC
  • GGCX
  • Peptidyl-glutamate 4-carboxylase
  • Vitamin K gamma glutamyl carboxylase
  • vitamin K-dependent gamma-carboxylase
  • VKCFD1

Background

Gamma-glutamyl carboxylase (GGCX) mediates the vitamin K-dependent carboxylation of glutamate residues to calcium binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. GGCX accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins. These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP) and bone matrix protein (MGP)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional GGCX Products

Array NBP2-98509JF635

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Bioinformatics

Gene Symbol GGCX