Reactivity | HuSpecies Glossary |
Applications | WB, Simple Western, IHC |
Clone | 2142A |
Clonality | Monoclonal |
Host | Rabbit |
Conjugate | Unconjugated |
Additional Information | Recombinant Monoclonal Antibody. |
Immunogen | Human DUX4 synthetic peptide |
Specificity | Detects human DUX4 in direct ELISAs and Western blots. |
Source | N/A |
Isotype | IgG |
Clonality | Monoclonal |
Host | Rabbit |
Purity Statement | Protein A or G purified from cell culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
Human Double homeobox 4 (aka DUX4) is a protein encoded by the DUX4 gene. This gene is located within a D4Z4 repeat array in chromosome 4q35. Each D4Z4 repeat unit has an open reading frame, DUX4, that contains two homeoboxes. Unregulated expression of DUX4 in muscle cells is the cause of facioscapulohumeral muscular dystrophy (FSHD), a common form of muscular dystrophy in adults that is one of the most prevalent genetic diseases of muscle.
Secondary Antibodies |
Isotype Controls |
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