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CHTF18 Antibody

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Immunocytochemistry/ Immunofluorescence: CHTF18 Antibody [NBP2-55371] - Staining of human cell line MCF7 shows localization to nucleoplasm.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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CHTF18 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LLLDILAPKLRPVSTQLYSTREKQQLASLVGTMLAYSLTYRQERTPDGQYIYRLEPNVEELCRFPELPARKPLTYQTKQL
Predicted Species
Rat (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHTF18
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
CHTF18 Recombinant Protein Antigen (NBP2-55371PEP)

Reactivity Notes

Mouse 88%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for CHTF18 Antibody

  • C16orf41
  • C321D2.2
  • C321D2.3 (novel protein)
  • C321D2.3
  • C321D2.4 (novel protein)
  • CHL12C321D2.4
  • chromosome 16 open reading frame 41
  • chromosome transmission fidelity protein 18 homolog
  • Ctf18
  • CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
  • EC 3.6.1
  • hCTF18
  • homolog of yeast CHL12
  • RUVBL
  • some homology with holliday junction DNA helicase RUVB like

Background

CTF18 (Chromosome Transmission Fidelity protein 18 homolog) is part of the CTF18-RFC (Replication Factor C) complex composed of CTF18, CTF8, DCC1, and four RFC subunits. This complex has been shown to be important for the establishment of sister chromatid cohesion and functions as a proliferating cell nuclear antigen (PCNA) loader for DNA synthesis. CTF18 is also known as hCTF18, CHTF18, CHL12, and RUVBL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol CHTF18