Independent Antibodies: Western Blot: CHTF18 Antibody [NBP1-03346] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. NBP1-03346 used for WB at 0.04 ...read more
Immunohistochemistry-Paraffin: CHTF18 Antibody [NBP1-03346] - Human stomach carcinoma. Antibody used at a dilution of 1:200 (1ug/ml).
The immunogen recognized by this antibody maps to a region between residue 25 and 75 of human chromosome transmission fidelity factor 18 using the numbering given in entry NP_071375.1 (GeneID 63922).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHTF18
Purity
Immunogen affinity purified
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chromosome transmission fidelity protein 18 homolog
Ctf18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
EC 3.6.1
hCTF18
homolog of yeast CHL12
RUVBL
some homology with holliday junction DNA helicase RUVB like
Background
CTF18 (Chromosome Transmission Fidelity protein 18 homolog) is part of the CTF18-RFC (Replication Factor C) complex composed of CTF18, CTF8, DCC1, and four RFC subunits. This complex has been shown to be important for the establishment of sister chromatid cohesion and functions as a proliferating cell nuclear antigen (PCNA) loader for DNA synthesis. CTF18 is also known as hCTF18, CHTF18, CHL12, and RUVBL.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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