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Cdk7 Antibody (MO-1)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clone
MO-1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Cdk7 Antibody (MO-1) Summary

Immunogen
Rabbits were immunized with a recombinant 221 amino acid fragment of the C terminus of Cdk7 recognizing a 40kD protein
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CDK7
Purity
Ammonium sulfate precipitation
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot : 1-10 ug /ml
Application Notes
.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline
Preservative
0.08% Sodium Azide
Purity
Ammonium sulfate precipitation

Alternate Names for Cdk7 Antibody (MO-1)

  • CAK1Xenopus laevis, cdk-activating kinase)
  • Cdk7
  • CDK-activating kinase
  • CDKN7
  • Cell division protein kinase 7
  • cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
  • cyclin-dependent kinase 7
  • EC 2.7.11
  • EC 2.7.11.22
  • EC 2.7.11.23
  • EC 2.7.11.24
  • MO15
  • p39 Mo15
  • serine/threonine kinase stk1,39 kDa protein kinase
  • serine/threonine protein kinase 1
  • serine/threonine protein kinase MO15
  • STK1
  • TFIIH basal transcription factor complex kinase subunit

Background

Cdk7 is encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CDK7