PHF1 Products

Description

PHF1 encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.

Bioinformatics

Uniprot	NP_077084 Human NP_077084.1 Human O43189 Human
Product By Gene ID	5252
Alternate Names	hPCl1 MTF2L2 PCL1 PHD finger protein 1 PHF2 Polycomb-like protein 1 Protein PHF1

Related PHF1 Blog Posts

Check out the latest blog posts on PHF1.

Microglia: pruning shears for homeostatic maintenance in the brain By Jennifer Sokolowski, MD, PhD.Microglia play a critical role in pruning neurons and synapses during homeostatic maintenance in the adult brain.1 A recent study by Ayata et al. (2018) identified regional differe...    Read more.

H3.1t - A testis-specific histone variant Histones are nuclear proteins essential for the storage and organization of genomic DNA as chromatin. Chromatin consists of DNA wrapped tightly around histone oligomers to form nucleosomes. In addition to compacting the genome, histones also regula...    Read more.

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