Mitofilin Products

Description

Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology. Mitofilin was originally described as heart muscle protein (HMP) because of its high expression in the heart.

Bioinformatics

Entrez	10989 Human 312444 Rat 76614 Mouse
Uniprot	AAH02412 Human NM_006839 Human NP_006830 Human Q16891 Human
Product By Gene ID	10989
Alternate Names	DKFZp779P1653 inner membrane protein, mitochondrial MGC111146 Mic 60 Mic60 MICOS Complex Subunit MIC60 mitochondrial (mitofilin) mitofilin Mitofilin motor protein p87/89 proliferation-inducing gene 4

Research Areas for Mitofilin

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Lipid and Metabolism
Mitochondrial Markers
Signal Transduction

Related Mitofilin Blog Posts

Check out the latest blog posts on Mitofilin.

Mitofilin and the Mitochondrial Inner Membrane Organizing System (MINOS) Mitofilin was originally described as a heart muscle protein due to its high expression in the heart. Recently, analysis of the human heart mitochondrial proteome demonstrated that Mitofilin is one of the most abundant mitochondrial proteins (1). Rese...    Read more.

Read more Mitofilin related blogs.