GPR78 Products

Description

The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene.

Bioinformatics

Entrez	27201 Human
Uniprot	NM_080819 Human NP_543009.2 Human Q96P69 Human
Product By Gene ID	27201
Alternate Names	G protein-coupled receptor 78 G-protein coupled receptor 78

Research Areas for GPR78

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GPCR
Lipid and Metabolism
Unfolded Protein Response

Related GPR78 Blog Posts

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GPR78 - an orphan receptor involved in psychiatric illness G-protein coupled receptor 78 (GPR78) was identified based on homology to other GPCR family members. The GPR78 gene encodes an orphan receptor protein that is 363 amino acids in length and contains the typical seven transmembrane domain found in G...    Read more.

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