Home » Diseases » Pachyonychia Congenita: Disease Bioinformatics
Submit your image related to Diseases to be featured!
Submit an Image

Get Social

Submit your Twitter account related to Pachyonychia Congenita to be featured!
Submit an Account

Blogs

 Submit your blog on Pachyonychia Congenita to be featured!
Submit a Blog

Events

 Submit your event on Pachyonychia Congenita to be featured!
Submit an Event

Videos

Submit your video on Pachyonychia Congenita to be featured!
Submit a Video

Charities

Submit your charity on Pachyonychia Congenita to be featured!
Submit a Charity

Pachyonychia Congenita: Disease Bioinformatics

Research of Pachyonychia Congenita has been linked to Thickened Nails, Nails, Malformed, Palmoplantar Keratosis, Nail Diseases, Ectodermal Dysplasia. The study of Pachyonychia Congenita has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Pachyonychia Congenita include Keratinization, Rna Interference, Pathogenesis, Cytolysis, Cornification. These pathways complement our catalog of research reagents for the study of Pachyonychia Congenita including antibodies and ELISA kits against INTERMEDIATE FILAMENT, KERATIN 6, KRT2-6A, K9, TYPE II KERATIN.

Top Research Reagents

We have 3363 products for the study of Pachyonychia Congenita that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Filaggrin Antibody
NBP1-87528
Immunohistochemistry-Paraffin: Filaggrin Antibody [NBP1-87528] - Analysis in human skin and liver tissues. Corresponding Filaggrin RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Filaggrin Antibody [NBP1-87528] - Staining of human gastrointestinal, liver, skin and testis using Anti-Filaggrin antibody NBP1-87528 (A) shows similar protein distribution across tissues to independent antibody NBP1-87527 (B).

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

     1 Review

7 Publications
Glutaminase Antibody
NBP1-89766
Immunohistochemistry-Paraffin: Glutaminase Antibody [NBP1-89766] - Staining in human kidney and skeletal muscle tissues using NBP1-89766 antibody. Corresponding GLS RNA-seq data are presented for the same tissues.Western Blot: Glutaminase Antibody [NBP1-89766] - Region-based expression of the pyruvate recycling pathway marker protein glutaminase (GLT) the VMN of icv Lz-pretreated male and female rats. GLT protein was measured by Western blot in the caudal (c; F(7,40) = 11.67; p < 0.0001) VMN of V/V, V/INS, Lz/V, and Lz/INS groups of male (M; left-hand side) and female (F; right-hand side) rats. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. For each VMN segment, data depict mean normalized GAD O.D. values +/- S.E.M. VMN = Ventromedial hypothalamic nucleus; V = Vehicle; L = letrozole; INS = insulin. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/33238883/) licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

5 Publications
Cytokeratin 6b Antibody
NBP2-14924
Western Blot: Cytokeratin 6b Antibody [NBP2-14924] - Sample (1 ug of whole cell lysate) A: HeLa 7. 5% SDS PAGE; antibody diluted at 1:5000.Immunocytochemistry/Immunofluorescence: Cytokeratin 6b Antibody [NBP2-14924] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

ENPP-1 Antibody
NBP2-27561
Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] - (4ug/ml) staining of paraffin embedded Human Thyroid Gland. Heat induced antigen retrieval with citrate buffer Ph 6, HRP-staining.Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] - Negative Control showing staining of paraffin embedded Human Thyroid Gland, with no primary antibody.

Goat Polyclonal
Species Human, Rat, Chicken
Applications WB, IHC, IHC-P

7 Publications
Cytokeratin, pan Antibody (AE-1/AE-3)
NBP2-29429
Pan-Cytokeratin was detected in immersion fixed paraffin-embedded sections of human Breast Tumor using Mouse Anti-Human Cytokeratin, pan Monoclonal Antibody (Catalog # NBP2-29429) at 1:500 at 37 ° Celsius for 4 minutes. Before incubation with the primary antibody, tissue underwent an all-in-one dewaxing and antigen retrieval preprocessing using PreTreatment Module (PT Module) and Dewax and HIER Buffer H (pH 9; Epredia Catalog # TA-999-DHBH). Tissue was stained using the Alexa Fluor™ 555 Goat anti-Mouse IgG Secondary Antibody at 1:100 at 37 ° Celsius for 2 minutes. (Yellow; Lunaphore Catalog # <A class=Cytokeratin, pan was detected in immersion fixed paraffin-embedded sections of mouse Kidney using Mouse Anti-Human/Mouse Cyokeratin, pan Monoclonal Antibody (Catalog #NBP2-29429) at 1:200 dilution at 37 ° Celsius for 4 minutes. Before incubation with the primary antibody, tissue underwent an all-in-one dewaxing and antigen retrieval preprocessing using PreTreatment Module (PT Module) and Dewax and HIER Buffer H (pH 9; Epredia Catalog # TA-999-DHBH).Tissue was stained using the Alexa Fluor™ 647 Goat anti-Mouse IgG Secondary Antibody at 1:200 at 37 ° Celsius for 2 minutes. (Yellow; Lunaphore Catalog # <A class=

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

71 Publications
Plasma Kallikrein/KLKB1 Antibody [Unconjugated]
AF2498

Goat Polyclonal
Species Mouse
Applications WB, IP

4 Publications
Polycystin-1/PKD1 Antibody [Unconjugated]
AF6270
Polycystin‑1/PKD1 was detected in immersion fixed HUVEC human umbilical vein endothelial cells using Sheep Anti-Human Polycystin‑1/PKD1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6270) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # <a class=

Sheep Polyclonal
Species Human
Applications ICC

Cytokeratin 17 Antibody
NBP2-38536
Immunohistochemistry-Paraffin: Cytokeratin 17 Antibody [NBP2-38536] - Analysis in human urinary bladder and liver tissues using NBP2-38536 antibody. Corresponding Cytokeratin 17 RNA-seq data are presented for the same tissues.Western Blot: Cytokeratin 17 Antibody [NBP2-38536] - Analysis in human cell lines HeLa and PC-3. Corresponding RNA-seq data are presented for the same cell lines. Loading control: Anti-HSP90B1.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     1 Review

TPD52 Antibody
NBP2-38952
Immunohistochemistry-Paraffin: TPD52 Antibody [NBP2-38952] - Staining in human prostate and skeletal muscle tissues using anti-TPD52 antibody. Corresponding TPD52 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: TPD52 Antibody [NBP2-38952] - Staining of human cerebral cortex, kidney, prostate and skeletal muscle using Anti-TPD52 antibody NBP2-38952 (A) shows similar protein distribution across tissues to independent antibody NBP1-85327 (B).

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Connexin 26/GJB2 Antibody - BSA Free
NBP2-41304
Western Blot: Connexin 26/GJB2 Antibody [NBP2-41304] - Western blotting analysis detects Cx26 using R(alpha)Cx26-Ct or R(alpha)Cx26-cl antibodies. (a) R(alpha)Cx26-Ct (A) and R(alpha)Cx26-cl (B) antibodies detected a specific 26kDa band on pig heart tissue lysates (lanes A and B are cropped blots obtained from the same gel). R(alpha)Cx26-cl recognized the 26kDa band on human and rat heart (H) lysates and on rat liver (L) sample (positive control) although two unspecific bands at molecular weights lower than 26kDa were detected. No bands were detected on smooth muscle (SM) tissue lysates (negative control) by R(alpha)Cx26-cl. R(alpha)GAPDH was used as protein loading control for rat tissue samples run on the same gel. Image collected and cropped by CiteAb from the following publication (nature.com/articles/s41598-018-32405-2), licensed under a CC-BY license.Immunocytochemistry/Immunofluorescence: Connexin 26/GJB2 Antibody [NBP2-41304] - Cx26 distribution at level of the cardiomyocyte cytoplasm. Confocal laser scanning microscopy: representative images of rat and pig heart sections. Double immunofluorescence analysis for Cx26 (red) and Cx43 (green) show a distinct cell localization of the two Cxs. (a) Three dimensional picture of the maximum intensity projection of the raw images of longitudinal rat heart section treated with R(alpha)Cx26-cl and M(alpha)Cx43. Scale bar: 20um. Image collected and cropped by CiteAb from the following publication (nature.com/articles/s41598-018-32405-2), licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Rat, Porcine
Applications WB, ELISA, ICC/IF

5 Publications
Cytokeratin 14 Antibody (LL002)
NBP2-34270
Immunocytochemistry/Immunofluorescence: Cytokeratin 14 Antibody (LL002) [NBP2-34270] - Immunofluorescence Analysis of A549 cells labeling CK14 with Cytokeratin 14 Antibody (LL002) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Red Dot (Red).Immunohistochemistry-Paraffin: Cytokeratin 14 Antibody (LL002) [NBP2-34270] - Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Cytokeratin 14 Antibody (LL002).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications Simple Western, Flow, ICC/IF

4 Publications
Cytokeratin 6 Antibody (SPM269)
NBP2-34358
Immunocytochemistry/Immunofluorescence: Cytokeratin 6 Antibody (SPM269) [NBP2-34358] - Immunofluorescence Analysis of RAW cells labeling KRT6 with Cytokeratin 6 Antibody (SPM269) followed by Goat anti-Mouse IgG-CF488 (Cyan). The nuclear counterstain is Red Dot (Red).Immunohistochemistry-Paraffin: Cytokeratin 6 Antibody (SPM269) [NBP2-34358] - Formalin-fixed, paraffin-embedded human Bladder Carcinoma stained with Cytokeratin 6 Monoclonal Antibody (SPM269).

Mouse Monoclonal
Species Human, Mouse
Applications Flow, ICC/IF, IHC

1 Publication
Cytokeratin 10 Antibody (3C2F5) - BSA Free
NBP2-61736
Western Blot: Cytokeratin 10 Antibody (3C2F5) [NBP2-61736] - Analysis using KRT10 mAb against HEK293 (1) and KRT10 (AA: 345-454)-hIgGFc transfected HEK293 (2) cell lysate.Immunohistochemistry-Paraffin: Cytokeratin 10 Antibody (3C2F5) [NBP2-61736] - Analysis of esophageal cancer tissues using KRT10 mouse mAb with DAB staining.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

3 Publications
Cytokeratin 5 Antibody - BSA Free
NBP2-61931
Western Blot: Cytokeratin 5 Antibody [NBP2-61931] - Total protein from human A431 cells and rat PC12 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-Cytokeratin 5 in 5% non-fat milk in TBST and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: Cytokeratin 5 Antibody [NBP2-61931] - A431 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X PBS + 0.1% Triton X-100. The cells were incubated with anti-Cytokeratin 5 at 5 ug/ml overnight at 4C and detected with an anti-rabbit DyLight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse DyLight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human, Rat
Applications WB, Flow, ICC/IF

2 Publications
Cytokeratin 16 Antibody (SC52-09)
NBP2-67559
Western Blot: Cytokeratin 16 Antibody (SC52-09) [NBP2-67559] - Analysis of Cytokeratin 16 on human skin lysates using anti-Cytokeratin 16 antibody at 1/1,000 dilution.Immunocytochemistry/Immunofluorescence: Cytokeratin 16 Antibody (SC52-09) [NBP2-67559] - Staining Cytokeratin 16 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human
Applications WB, Flow, ICC/IF


Related Genes

Pachyonychia Congenita has been researched against:

Related Pathways

Pachyonychia Congenita has been linked to:

Related Diseases

Pachyonychia Congenita has been studied in relation to diseases such as:

Alternate Names

Pachyonychia Congenita is also known as pachyonychia congenita, pachyonychia congenita, jadassohn-lewandowsky type, pachyonychia congenita type 1, pachyonychia congenita, jadassohn lewandowsky type, pachyonychia congenita jadassohn lewandowsky type, jackson-lawler type pachyonychia congenita, pachyonychia congenita, type 2 (disorder), jadassohn-lewandowski syndrome (pc-1), jackson-lawler syndrome (pc-2), jadassohn-lewandowsky syndrome, jadassohn lewandowsky syndrome, pachyonychia congenita, type 1, lewandowski kikolich syndrome, pc1.