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Epidermolysis Bullosa Acquisita: Disease Bioinformatics

Research of Epidermolysis Bullosa Acquisita has been linked to Epidermolysis Bullosa, Bullous Pemphigoid, Bulla, Autoimmune Reaction, Skin Diseases, Vesiculobullous. The study of Epidermolysis Bullosa Acquisita has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Epidermolysis Bullosa Acquisita include Pathogenesis, Localization, Complement Activation, Wound Healing, Immune Response. These pathways complement our catalog of research reagents for the study of Epidermolysis Bullosa Acquisita including antibodies and ELISA kits against NC1, LAMININ-1, FACTOR VIII, DST, C3.

Top Research Reagents

We have 3129 products for the study of Epidermolysis Bullosa Acquisita that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Ceruloplasmin Antibody (6C3K9)
NBP3-15868
Western Blot: Ceruloplasmin Antibody (6C3K9) [NBP3-15868] - Analysis of extracts of various cell lines, using Ceruloplasmin antibody (NBP3-15868) at 1:5000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.Immunohistochemistry: Ceruloplasmin Antibody (6C3K9) [Ceruloplasmin] - Immunohistochemistry analysis of paraffin-embedded Rat brain tissue using Ceruloplasmin Rabbit mAb at a dilution of 1:10000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

MHC Class I Antibody (OX18) - BSA Free
NB120-6405
Immunocytochemistry/Immunofluorescence: MHC Class I Antibody (OX18) [NB120-6405] - Major histocompatibility complex (MHC) I and II as well as Transporter associated with antigen presentation II (TAPII) were analyzed, using immunocytochemistry on rat Schwann cells (SCs). Corresponding merges are shown in the bottom rows. Treatment of SCs with IL-17 was performed at concentrations of 0.5 and 50 ng/mL. Graphs to the right show densitometry quantification. SCs showed expression of MHCI > TAPII > MHCII, which increased after IL-17 treatment. MHCI was mainly detected in the cytoplasm and the expression increased in a dose-dependent manner after IL-17 treatment, significant for 0.5 ng/mL and 50 ng/mL (**P <=0.01). Image collected and cropped by CiteAb from the following publication (https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-11-63), licensed under a CC-BY license.Immunohistochemistry-Paraffin: MHC Class I Antibody (OX18) [NB120-6405] - Analysis of FFPE rat brain cerebellum using MHC Class I (OK18) antibody at 1:200 on a Bond Rx autostainer (Leica Biosystems). The assay involved 20 minutes of heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0) and endogenous peroxidase quenching with peroxide block. The sections were incubated with primary antibody for 30 minutes and Bond Polymer Refine Detection (Leica Biosystems) with DAB was used for signal development followed by counterstaining with hematoxylin. Whole slide scanning and capturing of representative images was performed using Aperio AT2 (Leica Biosystems). Endothelial staining was observed. Staining was performed by Histowiz.

Mouse Monoclonal
Species Rat
Applications EM, ELISA, Flow

37 Publications
LAD1 Antibody
NBP1-86126
Western Blot: LAD1 Antibody [NBP1-86126] - Analysis in human cell lines A-431 and HEK293 using Anti-LAD1 antibody. Corresponding LAD1 RNA-seq data are presented for the same cell lines. Loading control: Anti-PFN1.Immunocytochemistry/Immunofluorescence: LAD1 Antibody [NBP1-86126] - Staining of human cell line MCF7 shows localization to actin filaments. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
ASCC3 Antibody
NBP1-88829
Immunohistochemistry-Paraffin: ASCC3 Antibody [NBP1-88829] - Staining of human cerebral cortex, colon, lymph node and testis using Anti-ASCC3 antibody NBP1-88829 (A) shows similar protein distribution across tissues to independent antibody NBP1-88854 (B).Western Blot: ASCC3 Antibody [NBP1-88829] - Western blot analysis of human skeletal muscle cell lysate (right lane). MWM in right lane (kDa). Western blot image submitted by a verified customer review.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     1 Review

ARFGEF1 Antibody
NBP1-88840
Western Blot: ARFGEF1 Antibody [NBP1-88840] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10<br/>Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: ARFGEF1 Antibody [NBP1-88840] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Dystonin Antibody
NBP1-89946
Immunocytochemistry/Immunofluorescence: Dystonin Antibody [NBP1-89946] - Staining of human cell line A-431 shows localization to nucleus & cytosol. Antibody staining is shown in green.Immunohistochemistry-Paraffin: Dystonin Antibody [NBP1-89946] - Staining of human tonsil shows low positivity in non-germinal center cells as expected.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

Fibronectin Antibody - BSA Free
NBP1-91258
Western Blot: Fibronectin Antibody - BSA Free [NBP1-91258] - VSOP observed in perivascular-restricted spinal cord lesions with intact BBB. Immunostaining for laminin (brown) shows vascular endothelium and glia limitans of a perivascular lesion, along with infiltrating cells and VSOP (blue). Image collected and cropped by CiteAb from the following publication (https://asn.sagepub.com/lookup/doi/10.1042/AN20120081), licensed under a CC-BY license.Immunocytochemistry/Immunofluorescence: Fibronectin Antibody - BSA Free [NBP1-91258] - NIH3T3 cells were fixed in 4% paraformaldehyde for 10 minutes and permeabilized in 0.05% Triton X-100 in PBS for 5 minutes. The cells were incubated with anti- NBP1-91258 at 1 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 100X objective and digitally deconvolved.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     11 Reviews

56 Publications
Recombinant Human KF1 GST (N-Term) Protein
H00007844-P01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human
Applications WB, ELISA, PA

Complement Component C3d Antibody [Unconjugated]
AF2655
Complement Component C3d was detected in perfusion fixed frozen sections of mouse kidney using Goat Anti-Mouse Complement Component C3d Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2655) overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href= Complement Component C3d was detected in perfusion fixed paraffin-embedded sections of rat kidney using Goat Anti-Mouse Complement Component C3d Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2655) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse, Rat
Applications WB, IHC

61 Publications
Desmoglein-1 Antibody [Unconjugated] - Propeptide
AF944
Desmoglein-1 was detected in immersion fixed paraffin-embedded sections of human skin using Goat Anti-Human Desmoglein-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF944) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, IHC

4 Publications
TNF-alpha [Unconjugated]
210-TA
Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     3 Reviews

822 Publications
ARID2 Antibody (7311)
NBP2-43567
Western Blot: ARID2 Antibody (7311) [NBP2-43567] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with ARID2 antibody. (WT: wild type; KO: knockout)Western Blot: ARID2 Antibody (7311) [NBP2-43567] - Non-transfected (-) and transfected (+) 293T whole cell extracts (50 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with ARID2 antibody (7311) diluted at 1:1000. HRP-conjugated anti-mouse IgG antibody was used to detect the primary antibody.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ICC/IF, KO

1 Publication
CDP/CUTL1 Antibody (2A10)
H00001523-M01
Western Blot: CDP/CUTL1 Antibody (2A10) [H00001523-M01] - Analysis of CUX1 expression in transfected 293T cell line by CUTL1 monoclonal antibody (M01), clone 2A10.Lane 1: CUX1 transfected lysate(77.2 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: CDP/CUTL1 Antibody (2A10) [H00001523-M01] - Analysis of monoclonal antibody to CUTL1 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

     1 Review

4 Publications
Cytokeratin 20 Antibody (SA35-03)
NBP2-67309
Western Blot: Cytokeratin 20 Antibody (SA35-03) [NBP2-67309] - Analysis of Cytokeratin 20 on CRC cell lysates with Rabbit anti-Cytokeratin 20 antibody at 1/5,000 dilution. Lysates/proteins at 10 ug/Lane. Predicted band size: 48 kDa Observed band size: 48 kDa Exposure time: 30 seconds; 10% SDS-PAGE gel. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody at 1/5,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:300,000 dilution was used for 1 hour at room temperature.Immunocytochemistry/Immunofluorescence: Cytokeratin 20 Antibody (SA35-03) [NBP2-67309] - Staining Cytokeratin 20 in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Rat
Applications WB, Flow, ICC/IF

Collagen XVII Antibody (SR46-05)
NBP2-67316
Immunocytochemistry/Immunofluorescence: Collagen XVII Antibody (SR46-05) [NBP2-67316] - Staining Collagen XVII in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Western Blot: Collagen XVII Antibody (SR46-05) [NBP2-67316] - Analysis of Collagen XVII on different lysates with Rabbit anti-Collagen XVII antibody at 1/5,000 dilution.Lane 1: A431 cell lysate (15 ug/Lane)Lane 2: Mouse skin tissue lysate (20 ug/Lane)Lane 3: Rat skin tissue lysate (20 ug/Lane)Predicted band size: 148 kDaObserved band size: 130、180 kDaExposure time: 40 seconds; ECL: K1802;4-20% SDS-PAGE gel.Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody at 1/5,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1/50,000 dilution was used for 1 hour at room temperature.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
CHN 1 Antibody (OTI2G6) - Azide and BSA Free
NBP2-70411
Western Blot: CHN 1 Antibody (OTI2G6) - Azide and BSA Free [NBP2-70411] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CHN 1.Immunocytochemistry/Immunofluorescence: CHN 1 Antibody (OTI2G6) - Azide and BSA Free [NBP2-70411] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY CHN 1.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

Complement Component C5aR1 Antibody (347234) [Unconjugated]
MAB36481
HEK293 human embryonic kidney cell line transfected with either (A) human C5aR or (B) irrelevant protein and eGFP was stained with Mouse Anti-Human C5aR Monoclonal Antibody (Catalog # MAB36481) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=Complement Component C5aR1 was detected in immersion fixed U937 human histiocytic lymphoma cell line (positive) and SH-SY5Y human neuroblastoma cell line (negative control) using Mouse Anti-Human Complement Component C5aR1 Monoclonal Antibody (Catalog # MAB36481) at 8 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications Flow, IHC, CyTOF-ready


Related Genes

Epidermolysis Bullosa Acquisita has been researched against:

Related Pathways

Epidermolysis Bullosa Acquisita has been linked to:

Related Diseases

Epidermolysis Bullosa Acquisita has been studied in relation to diseases such as:

Related PTMs

Epidermolysis Bullosa Acquisita has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Epidermolysis Bullosa Acquisita is also known as epidermolysis bullosa acquisita, acquired epidermolysis bullosa (disorder), acquired form of epidermolysis bullosa, acquired epidermolysis bullosa, eb acquisita, eba.