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Chronic Progressive External Ophthalmoplegia: Disease Bioinformatics

Research of Chronic Progressive External Ophthalmoplegia has been linked to Ophthalmoplegia, External Ophthalmoplegia, Myopathy, Mitochondrial Myopathies, Mitochondrial Diseases. The study of Chronic Progressive External Ophthalmoplegia has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Chronic Progressive External Ophthalmoplegia include Pathogenesis, Oxidative Phosphorylation, Cardiac Conduction, Transport, Dna Replication. These pathways complement our catalog of research reagents for the study of Chronic Progressive External Ophthalmoplegia including antibodies and ELISA kits against ADENINE NUCLEOTIDE TRANSLOCATOR 1, DNA POLYMERASE GAMMA, STRABISMUS, POL GAMMA, MITOCHONDRIAL DNA POLYMERASE GAMMA.

Top Research Reagents

We have 1430 products for the study of Chronic Progressive External Ophthalmoplegia that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Recombinant Human COX8A GST (N-Term) Protein
H00001351-P01
SDS-Page: COX8A Recombinant Protein [H00001351-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human
Applications WB, ELISA, PA

PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) - BSA Free
NB100-2737
Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node. In benign lymph node, TP expression highlights the meshwork of macrophages (arrow in inset; 400x) and endothelial cells (arrowhead in inset; 400x). Images are from an Olympus BX41 microscope (Olympus Corp., Tokyo, Japan) processed with Qcapture Pro 5.1 (QImaging, Surrey, BC, Canada). Image collected and cropped by CiteAb from the following publication (https://www.hindawi.com/journals/ah/2011/875135/) licensed under a CC-BY license.Immunohistochemistry: PD-ECGF/Thymidine Phosphorylase Antibody (PGF 44C) [NB100-2737] - Immunohistochemical staining of thymidine phosphorylase (TP) expression and related markers in benign lymph node in lymph node with malignant mycosis fungoides/Sezary syndrome cells (LN-MF). CD21 is negative in this case of LN-MF. Images are from an Olympus BX41 microscope (Olympus Corp., Tokyo, Japan) processed with Qcapture Pro 5.1 (QImaging, Surrey, BC, Canada). Image collected and cropped by CiteAb from the following publication (https://www.hindawi.com/journals/ah/2011/875135/) licensed under a CC-BY license.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
COX5A Antibody
NBP1-32550
Western Blot: COX5A Antibody [NBP1-32550] - Various whole cell extracts (30 ug) were separated by 15% SDS-PAGE, and the membrane was blotted with COX5A antibody [N1C3] diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.Immunocytochemistry/Immunofluorescence: COX5A Antibody [NBP1-32550] - A431.

Rabbit Polyclonal
Species Human, Mouse, Zebrafish
Applications WB, ICC/IF, IHC

3 Publications
DNA Polymerase gamma Antibody
NBP1-52300
Western Blot: DNA Polymerase gamma Antibody [NBP1-52300] - Analysis of anti-POLG antibody with (30 ug of whole cell lysate). A: 293T. 5% SDS PAGE. POLG antibody diluted at 1:5000.Immunocytochemistry/Immunofluorescence: DNA Polymerase gamma Antibody [NBP1-52300] - Analysis of anti-POLG antibody with methanol-fixed HeLa cell at 1:200 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

5 Publications
PRPF6 Antibody
NBP1-92298
Immunohistochemistry-Paraffin: PRPF6 Antibody [NBP1-92298] - Staining in human fallopian tube and pancreas tissues using anti-PRPF6 antibody. Corresponding PRPF6 RNA-seq data are presented for the same tissues.Western Blot: PRPF6 Antibody [NBP1-92298] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

CHMP1B Antibody
NBP2-37986
Immunocytochemistry/Immunofluorescence: CHMP1B Antibody [NBP2-37986] - Staining of human cell line U-2 OS shows localization to nucleus & midbody. Antibody staining is shown in green.Immunohistochemistry-Paraffin: CHMP1B Antibody [NBP2-37986] - Staining of human thyroid gland shows high expression.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

GM-CSF [Unconjugated]
7954-GM/CF
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human
Applications BA

3 Publications
LAMC2 Antibody (CL2980)
NBP2-42388
Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

4 Publications
MRRF Antibody (OTI1D5)
NBP2-45434
Western Blot: MRRF Antibody (1D5) [NBP2-45434] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MRRF.Immunohistochemistry: MRRF Antibody (1D5) [NBP2-45434] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

Mouse monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

CPOX Antibody (36B10) - BSA Free
NBP2-59438
Western Blot: CPOX Antibody (36B10) [NBP2-59438] - Lane 1: Recombinant protein CPOX, Lane 2: 293T cell lysates, Lane 3: HepG2 cell lysates, Lane 4: A549 cell lysates, Lane 5: Jurkat cell lysates, Lane 6: K562 cell lysates, Lane 7: LnCaP cell lysatesImmunocytochemistry/Immunofluorescence: CPOX Antibody (36B10) [NBP2-59438] - Analysis of CPOX in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CPOX antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

1 Publication
ERG Antibody - BSA Free
NBP2-60655
Western Blot: ERG Antibody [NBP2-60655] - Total protein from Human THP-1, Jurkat and K562 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-ERG in blocking buffer and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: ERG Antibody [NBP2-60655] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-ERG at 5 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Cytochrome c Antibody (7H8.2C12) - BSA Free
NB100-56503
Western Blot: Cytochrome c Antibody (7H8.2C12) [NB100-56503] - Metformin activates apoptotic cell death; Right panel: MCF-7 cells were kept in the presence or absence of metformin for 20 days and then processed to obtain mitochondrial or whole cellular extracts. BAX and CYCS expression levels were determined by Western blot as indicated under Material and Methods. Densitometric analysis of the gels was performed as indicated under Material and Methods. PHB and CDK4 were used as purity and loading controls. Image collected and cropped by CiteAb from the following publication (https://www.mdpi.com/2073-4409/8/1/49), licensed under a CC-BY license.Immunocytochemistry/Immunofluorescence: Cytochrome c Antibody (7H8.2C12) [NB100-56503] - p73 was detected in immersion fixed Hela human cell line using NB100-56503 at 25 ug/ml for 3 hours at room temperature. Cells were stained using the NorthernLights(TM) 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Staining was observed in the cytoplasm and mitochondria.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

61 Publications
Adenine Nucleotide Translocase 1 Antibody - Azide and BSA Free
NBP2-92642
Western Blot: Adenine Nucleotide Translocase 1 Antibody [NBP2-92642] - Analysis of extracts of various cell lines, using SLC25A4/ANT1 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit. Exposure time: 10s.Immunocytochemistry/Immunofluorescence: Adenine Nucleotide Translocase 1 Antibody [NBP2-92642] - Analysis of PC-12 cells using SLC25A4/ANT1 Rabbit pAb at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

PEO1 Antibody - Azide and BSA Free
NBP2-93513
Western Blot: PEO1 Antibody [NBP2-93513] - Western blot analysis of extracts of various cell lines, using PEO1 antibody (NBP2-93513) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.Western Blot: PEO1 Antibody [NBP2-93513] - Western blot analysis of extracts of Rat kidney, using PEO1 antibody (NBP2-93513) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB

POLG2 Antibody - BSA Free
NBP2-94064
Western Blot: POLG2 Antibody [NBP2-94064] - Analysis of extracts of various cell lines, using POLG2 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 90s.Immunocytochemistry/Immunofluorescence: POLG2 Antibody [NBP2-94064] - Analysis of MCF7 cells using POLG2 . Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC


Related Genes

Chronic Progressive External Ophthalmoplegia has been researched against:

Related Pathways

Chronic Progressive External Ophthalmoplegia has been linked to:

Related Diseases

Chronic Progressive External Ophthalmoplegia has been studied in relation to diseases such as:

Related PTMs

Chronic Progressive External Ophthalmoplegia has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Chronic Progressive External Ophthalmoplegia is also known as chronic progressive external ophthalmoplegia, progressive external ophthalmoplegia, cpeo, peo, progressive external ophthalmoplegia (disorder).