COUP-TF I/NR2F1 Antibody (H8132) [Unconjugated] Summary
Source N/A
Isotype IgG2a
Clonality Monoclonal
Host Mouse
Gene NR2F1
Innovator's Reward Test in a species/application not listed above to receive a full credit towards a future purchase.
Applications/Dilutions
Dilutions
Immunohistochemistry 5-15 ug/mL Immunoprecipitation Western Blot
Reviewed Applications
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Packaging, Storage & Formulations
Storage Store the unopened product at -70 ยฐC. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer A liquid formulation in physiologic saline with 0.1% NaN3 .
Preservative 0.1% Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for COUP-TF I/NR2F1 Antibody (H8132) [Unconjugated]
Background
Chicken ovalbumin upstream promoter transcription factor I (COUP-TF I, EAR3, COUP-TFA; NR2F1) is a member of the orphan nuclear receptor family. COUP-TF I is expressed in specific regions of the rostral brain. COUP-TF I has varied roles in the development of the peripheral nervous system, such as early regionalization of the neocortex, differentiation of subplate neurons and guidance of thalamocortical axons. COUP-TFs have been shown to interact with a number of other nuclear receptors.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Applications: ELISA
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Publications for COUP-TF I/NR2F1 Antibody (PP-H8132-00)(13)
We have publications tested in 3 confirmed species: Human, Mouse, Rat.
We have publications tested in 5 applications: ChIP, Flow Cytometry, ICC, IHC, Western Blot.
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10 of 13.
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Publications using PP-H8132-00
Applications
Species
D Jgamadze, JT Lim, Z Zhang, PM Harary, J Germi, K Mensah-Bro, CD Adam, E Mirzakhali, S Singh, JB Gu, R Blue, M Dedhia, M Fu, F Jacob, X Qian, K Gagnon, M Sergison, O Fruchet, I Rahaman, H Wang, F Xu, R Xiao, D Contreras, JA Wolf, H Song, GL Ming, HI Chen Structural and functional integration of human forebrain organoids with the injured adult rat visual system Cell Stem Cell, 2023-02-02;30(2):137-152.e7. 2023-02-02 [PMID: 36736289] (IHC, Human) IHC
Human
ES Liau, S Jin, YC Chen, WS Liu, M Calon, S Nedelec, Q Nie, JA Chen Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons Oncogene, 2023-01-03;14(1):46. 2023-01-03 [PMID: 36596814]
D Yang, J Gomez-Garc, S Funakoshi, T Tran, I Fernandes, GD Bader, MA Laflamme, GM Keller Modeling human multi-lineage heart field development with pluripotent stem cells Cell Stem Cell, 2022-09-01;29(9):1382-1401.e8. 2022-09-01 [PMID: 36055193] (ICC, Human) ICC
Human
Wang T, Wang Z, de Fabritus L Et al. 1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development Developmental cell 2021-11-22 [PMID: 34762852]
J Feng, WH Hsu, D Patterson, CS Tseng, HW Hsing, ZH Zhuang, YT Huang, A Faedo, JL Rubenstein, J Touboul, SJ Chou COUP-TFI specifies the medial entorhinal cortex identity and induces differential cell adhesion to determine the integrity of its boundary with neocortex Science Advances, 2021-07-02;7(27):. 2021-07-02 [PMID: 34215582] (ChIP, Mouse) ChIP
Mouse
K Zhang, F Yu, J Zhu, S Han, J Chen, X Wu, Y Chen, T Shen, J Liao, W Guo, X Yang, R Wang, Y Qian, J Yang, L Cheng, Y Zhao, CC Hui, J Li, G Peng, S He, N Jing, K Tang Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation Cell Rep, 2020-04-21;31(3):107521. 2020-04-21 [PMID: 32320667] (ICC, Human) ICC
Human
Zeda Zhang, Chuanli Zhou, Xiaoling Li, Spencer D. Barnes, Su Deng, Elizabeth Hoover et al. Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation Cancer Cell 2020-04-13 [PMID: 32220301]
M Laugsch, M Bartusel, R Rehimi, H Alirzayeva, A Karaolidou, G Crispatzu, P Zentis, M Nikolic, T Bleckwehl, P Kolovos, WFJ van Ijcken, T ล ari?, K Koehler, P Frommolt, K Lachlan, J Baptista, A Rada-Igles Modeling the Pathological Long-Range Regulatory Effects of Human Structural Variation with Patient-Specific hiPSCs Cell Stem Cell, 2019-04-11;0(0):. 2019-04-11 [PMID: 30982769] (Flow Cytometry, ICC, Human) Flow Cytometry, ICC
Human
R Smith, YT Huang, T Tian, D Vojtasova, O Mesalles-N, SM Pollard, T Pratt, DJ Price, V Fotaki The transcription factor Foxg1 promotes optic fissure closure in the mouse by suppressing Wnt8b in the nasal optic stalk J. Neurosci., 2017-07-20;0(0):. 2017-07-20 [PMID: 28729440] (IHC, Mouse) IHC
Mouse
Duchez A, Boudreau L, Bollinger J, Belleannee C, Cloutier N, Laffont B, Mendoza-Villarroel R, Levesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay J, Poubelle P, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb M, Boilard E Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA. Proc Natl Acad Sci U S A, 2015-06-23;112(27):E3564-73. 2015-06-23 [PMID: 26106157] (IHC, Human) IHC
Human
Sosa M, Parikh F, Maia A, Estrada Y, Bosch A, Bragado P, Ekpin E, George A, Zheng Y, Lam H, Morrissey C, Chung C, Farias E, Bernstein E, Aguirre-Ghiso J NR2F1 controls tumour cell dormancy via SOX9- and RARbeta-driven quiescence programmes. Nat Commun, 2015-01-30;6(0):6170. 2015-01-30 [PMID: 25636082] (Western Blot, Human, Mouse) Western Blot
Human, Mouse
Pattabiraman K, Golonzhka O, Lindtner S, Nord A, Taher L, Hoch R, Silberberg S, Zhang D, Chen B, Zeng H, Pennacchio L, Puelles L, Visel A, Rubenstein J Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex. Neuron, 2014-05-08;82(5):989-1003. 2014-05-08 [PMID: 24814534] (ChIP, Mouse) ChIP
Mouse
Kuo TY, Hong CJ, Hsueh YP Bcl11A/CTIP1 regulates expression of DCC and MAP1b in control of axon branching and dendrite outgrowth. Mol. Cell. Neurosci., 2009-07-17;42(3):195-207. 2009-07-17 [PMID: 19616629] (Western Blot, Rat) Western Blot
Rat
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Review for COUP-TF I/NR2F1 Antibody (PP-H8132-00) (1)
3 1
Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Human.
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Reviews using PP-H8132-00:
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Date
Details
3
reviewed by:
ICC
Human
11/16/2023
Summary
Application Immunocytochemistry Sample Tested IGR39 human melanoma cell line Species Human Lot A-2
Comments
Comments ***Bio-Techne Response: This review was submitted through the legacy Novus Innovators Program, reflecting a new species or application tested on a primary antibody.***
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