XYLT2 Products

Description

The protein encoded by the XYLT2 gene is an isoform of xylosyltransferase, which belongs to a family ofglycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein andinitiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparansulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is adiagnostic marker for the determination of sclerotic activity in systemic sclerosis. (provided by RefSeq)

Bioinformatics

Entrez	64132 Human
Uniprot	NM_022167 Human Q9H1B5 Human
Product By Gene ID	64132
Alternate Names	EC 2.4.2.26 Peptide O-xylosyltransferase 1 PXYLT2 XT2UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase xylosyltransferase 2 xylosyltransferase IIXT-IIprotein xylosyltransferase 2 XylT-II xylT-II