Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
7328 |
Alternate Names |
- EC 6.3.2.19
- UBC8E2-20K
- UBCH
- UBCH2
- UbcH2
- Ubiquitin carrier protein H
- ubiquitin-conjugating enzyme E2 H
- Ubiquitin-conjugating enzyme E2-20K
- ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8)
- ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
- Ubiquitin-protein ligase H
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