Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
SUMO4 is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
387082 |
| Alternate Names |
- dJ281H8.4
- IDDM5
- small ubiquitin-like modifier 4 protein
- Small ubiquitin-like protein 4
- small ubiquitin-related modifier 4
- SMT3 suppressor of mif two 3 homolog 2
- SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
- SMT3 suppressor of mif two 3 homolog 4 (yeast)
- SMT3H4
- SUMO-4
|
Research Areas for SUMO4
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Protein Phosphatase
