Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, RM
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Mu
Applications: PAGE
Species: Hu
Applications: PAGE
Description
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
6697 |
| Alternate Names |
- EC 1.1.1.153
- SDR38C1
- sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
- sepiapterin reductase
- short chain dehydrogenase/reductase family 38C, member 1
|
![Enzyme Activity SPR [Unconjugated]](http://images.novusbio.com/fullsize2/SPR_10209SP_2944.jpg)
![SDS-PAGE SPR [Unconjugated]](http://images.novusbio.com/fullsize2/SPR_10209SP_2817.jpg)